Results 121 to 130 of about 106,593 (352)

Yield of Whole Genome Sequencing for Pathogenic Single Nucleotide Variants in Congenital Heart Disease: A Systematic Review and Meta‐Analysis

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa, Parisa Najjariasl, Faezeh Aghajani, Enaja V. Sambatur, Andrew Rodenbarger, Stephanie Guseh, Amy E. Roberts, Alireza A. Shamshirsaz   +7 more
wiley   +1 more source

Chronic inflammation following hernia repair and cancer risk: A nationwide study

Surgery Open Science
Purpose: Implantation of mesh in patients undergoing hernia surgery or prolonged inflammation due to postoperative complication may be associated with increased risk of cancer.We aim to test whether implementation of mesh or complicated postoperative ...
Malene Broholm, MD, PhD, Ismail Gögenur, MD, DMSc, Lau Caspar Thygesen, Cand.Scient.san.publ, PhD, Frederik Helgstrand, MD, PhD   +3 more
doaj   +1 more source

The Expanding Role of Gene Sequencing in Shaping Fetal Therapies: Clinical and Ethical Considerations

Prenatal Diagnosis, EarlyView.
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear, Beltran Borges, Billie R. Lianoglou, Tony Lum, Emma Canepa, Jennifer L. Cohen, Julia E. H. Brown, Akos Herzeg   +7 more
wiley   +1 more source

Laparoscopic Treatment Experience In Morgagni Hernia Repair In Children [PDF]

, 2019
Ali İhsan Anadolulu, Gonca Gerçel, Osman Hakan Kocaman   +2 more
openalex   +1 more source

Edoardo Bassini (1844-1924): father of modern-day hernia surgery. [PDF]

, 2013
According to Roman scripture, it was Celsus who attempted the first inguinal hernia repair in history during the first century A.D. His attempts were unsuccessful and resulted in an early recurrence of the hernia, which eventually led to the patient’s ...
Cowan, MD, Scott W., Lavu, MD, Harish, Rosato, MD, Ernest L., Tan, B.S., Wei Phin, Yeo, MD, Charles J.   +4 more
core   +1 more source

Clinical Utility of Nuchal Translucency Measurement in First‐Trimester Ultrasound Screening in a Setting With First‐Tier NIPT for Aneuploidy Screening

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To investigate the additional clinical value of nuchal translucency (NT) measurement at the first‐trimester anomaly scan (FTAS) in a setting with first‐tier non‐invasive prenatal testing (NIPT). Method This nationwide prospective cohort study, part of the IMITAS study on FTAS implementation, included all pregnancies with increased NT
Eline E. R. Lust, Kim Bronsgeest, Lidewij Henneman, Neeltje M. T. H. Crombag, Caterina M. Bilardo, Robert‐Jan H. Galjaard, Esther Sikkel, Audrey B. C. Coumans, Ayten Elvan‐Taşpınar, Sander Galjaard, Attie T. J. I. Go, Gwendolyn T. R. Manten, Eva Pajkrt, Elisabeth van Leeuwen, Monique C. Haak, Mireille N. Bekker   +15 more
wiley   +1 more source

Incisional Hernia Repair: Laparoscopy versus Open Surgery - A Prospective Study

, 2023
LAMARA Abdelhak, BENYARABAH Saliha, GUADDA Mounir, BELHATEM Mohamed Salah, NINI Badereddine, BOUKHENE Mohamed, MEDJAHDI Sid Ahmed, NIBOUCHA Mohamed Lamine, Meriem Rayen LAMARA   +8 more
openalex   +1 more source

Understanding sports hernia (athletic pubalgia) - The anatomic and pathophysiologic basis for abdominal and groin pain in athletes [PDF]

, 2008
Recent publicity and some scientific reports suggest increasing success in treating an entity called “sports hernia” - more accurately named athletic pubalgia.
Devon, Octavia, Horner, Marcia, Jain, Nikhil, Lauencin, Cato, Meyers, William C., Yoo, Edward, Zoga, Adam   +6 more
core   +1 more source

Lipid Nanoparticles Delivering ClpP‐mRNA Suppress Pyroptosis and Senescence in Intervertebral Disc Degeneration via mTOR/BNIP3‐Activated Mitophagy

Rare Metals, EarlyView.
ABSTRACT Intervertebral disc degeneration (IDD) is a predominant cause of low back pain, significantly impacting quality of life. Mitochondrial fitness is essential in the progression of IDD, as it regulates cellular senescence and pyroptosis. This study investigates the role of mitochondrial caseinolytic protease P (ClpP) in alleviating senescence and
Kun Wang, Zhiqiang Wang, Tong Zhang, Shicheng Qiu, Guang Yang, Yanzheng Gao, Xiaofeng Lian, Xin Peng   +7 more
wiley   +1 more source

Association between fetal brain diffusion‐weighted imaging and postnatal neurodevelopmental outcome after prenatal myelomeningocele repair

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective Myelomeningocele (MMC) is associated with significant alterations of the brain microstructure, which can impair long‐term neurodevelopmental outcomes. By measuring the random displacement of water molecules within the brain, magnetic resonance imaging (MRI)‐based diffusion‐weighted imaging (DWI) can provide objective metrics, such as
R. Corroenne, T. A. G. M. Huisman, W. E. Whitehead, A. A. Nassr, J. L. Munoz, J. Castillo, H. Castillo, R. M. Johnson, R. V. Donepudi, M. A. Belfort, M. Sanz‐Cortes   +10 more
wiley   +1 more source