Results 51 to 60 of about 51,349 (307)

SETD1A Regulates Glycolysis and Senescence of Nucleus Pulposus Cells via H3K4me3–HELZ2/PPARα‐HIF1α Axis to Drive Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
SETD1A is a key epigenetic regulator in NPCs during IDD. In normal NPCs, it sustains H3K4me3–HELZ2/PPARα–HIF1α signaling to maintain glycolytic energy metabolism and proliferation. In degenerated NPCs, reduced SETD1A disrupts this axis, impairing glycolysis and accelerating senescence, highlighting a promising therapeutic target for IDD.
Jiawei Fu   +11 more
wiley   +1 more source

The use of biological meshes in diaphragmatic defects – An evidence-based review of the literature

open access: yesFrontiers in Surgery, 2015
The widespread use of meshes for hiatal hernia repair has emerged in the era of laparoscopic surgery, although sporadic cases of mesh augmentation of traumatic diaphragmatic rupture have been reported. The indications for biologic meshes in diaphragmatic
Stavros Athanasios Antoniou   +3 more
doaj   +1 more source

Cost analysis of incisional hernia repair by suture or mesh

open access: yes, 2003
The objective was to make a cost analysis of incisional hernia repair by suture repair or prosthetic mesh repair. The study included 44 patients who underwent hernia repair between 1991 and 2000.
Jönsson, L,, Wimo, A,, Israelsson, LA
core   +1 more source

Mesh fixation techniques for inguinal hernia repair: an overview of systematic reviews of randomised controlled trials [PDF]

open access: yes, 2022
PURPOSE: Inguinal hernia repair using surgical mesh is a very common surgical operation. Currently, there is no consensus on the best technique for mesh fixation.
Imamura, Mari   +13 more
core   +1 more source

Dynamic Self‐Clickable Decellularized Matrix Hydrogels for Regulating Vascularity and Enhancing Muscle Regeneration

open access: yesAdvanced Science, EarlyView.
Dynamic decellularized hydrogels are prepared using bovine decellularized small intestine submucosa (SIS) norbornene (dSIS‐NB). Bovine dSIS contained significant amounts of disulfide‐rich fibrillin‐I, enabling ‘self‐clickable’ thiol‐norbornene gelation and spatiotemporal tuning of hydrogel physicochemical properties.
Van Thuy Duong   +4 more
wiley   +1 more source

LONG-TERM RESULTS OF VARIOUS TREATMENT OPTIONS FOR VENTRAL HERNIAS

open access: yesКубанский научный медицинский вестник, 2017
In modern herniology tension free technic of hernia repair is a leading, thanks mainly to fewer recurrences. However, hernia repair breaks anatomy and functionality of the anterior abdominal wall, which leads to a deterioration in the quality of life of ...
S. E. GUMENYUK   +7 more
doaj   +1 more source

Laparoscopic inguinal hernia repair- Transabdominal preperitoneal (TAPP) versus totally extraperitoneal (TEP) approach: A comparative analysis

open access: yesMedical Journal of Dr. D.Y. Patil Vidyapeeth, 2023
Background and Aim: Totally extraperitoneal (TEP) repair and transabdominal preperitoneal (TAPP) repair are the two standardized laparoscopic techniques for inguinal hernia repair.
Munish Trehan   +6 more
doaj   +1 more source

Amyand’s hernia : a case report [PDF]

open access: yes, 2013
The presence of vermiform appendix, whether normal or inflamed in the inguinal hernia, is referred to as Amyand’s hernia. This is rare occurring in about 1% of inguinal hernias in adults.
Muscat, Peter
core  

Do postoperative complications correlate to chronic pain following inguinal hernia repair? : a prospective cohort study from the Swedish hernia register

open access: yes, 2023
Purpose: To analyse if postoperative complications constitute a predictor for the risk of developing long-term groin pain. Methods: Population-based prospective cohort study of 30,659 patients operated for inguinal hernia 2015–2017 included in the ...
Franneby, U.   +5 more
core   +1 more source

Multiscale Architecture and Mechanics of the Cell Nucleus: Implications for Disease, Bioengineering and Nanomedicine

open access: yesAdvanced Science, EarlyView.
Nuclear mechanical properties are inherently scale‐dependent, arising from a hierarchical architecture that spans DNA, chromatin, the nuclear envelope, and condensates. Experimental techniques and theoretical models are integrated into a cohesive multiscale framework linking nanoscale structural features to organelle‐level mechanical behavior.
Xinran Liu   +15 more
wiley   +1 more source

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