Results 181 to 190 of about 4,712 (211)

Congenital diaphragmatic hernia

Paediatric Respiratory Reviews, 2002
Congenital diaphragmatic hernia (CDH) is a lethal human birth defect. Hypoplastic lung development is the leading contributor to its 30-50% mortality rate. Efforts to improve survival have focused on fetal surgery, advances in intensive care and elective delivery at specialist centres following in utero diagnosis.
Nicola P, Smith, Edwin C, Jesudason, Paul D, Losty   +2 more
  +7 more sources

Congenital diaphragmatic hernia

Nature Reviews Disease Primers, 2022
Congenital diaphragmatic hernia (CDH) is a rare birth defect characterized by incomplete closure of the diaphragm and herniation of fetal abdominal organs into the chest that results in pulmonary hypoplasia, postnatal pulmonary hypertension owing to vascular remodelling and cardiac dysfunction. The high mortality and morbidity rates associated with CDH
Augusto Zani, Wendy K. Chung, Jan Deprest, Matthew T. Harting, Tim Jancelewicz, Shaun M. Kunisaki, Neil Patel, Lina Antounians, Pramod S. Puligandla, Richard Keijzer   +9 more
openaire   +2 more sources

Congenital Diaphragmatic Hernia

New England Journal of Medicine, 2017
A baby girl was delivered by cesarean section at 36 weeks of gestation because of an antenatal diagnosis of congenital diaphragmatic hernia.
Jared, Klein, Megan, Sirota
openaire   +2 more sources

Congenital Diaphragmatic Hernia

Surgical Clinics of North America, 1985
Congenital diaphragmatic hernia continues to be a critical problem in neonatal surgery. Despite the apparent simplicity of the anatomic defect, the physiology is complex, and survival remains uncertain. Surgical success has been achieved, but we recognize that the barrier to survival is pulmonary parenchymal and vascular hypoplasia as well as the ...
M L, Cullen, M D, Klein, A I, Philippart
openaire   +2 more sources

Congenital diaphragmatic hernia

Early Human Development, 2014
There is a paucity of level 1 and level 2 evidence for best practice in surgical management of CDH. Antenatal imaging and prognostication is developing. Observed to expected lung-to-head ratio on ultrasound allows better predictive value over simple lung-to-head ratio.
Lisette, Leeuwen, Dominic A, Fitzgerald
openaire   +4 more sources

Congenital Diaphragmatic Hernia

Surgical Clinics of North America, 1981
Surgical intervention for congenital diaphragmatic hernia is urgent, but success depends more on preoperative and postoperative management of the associated physiologic derangements. Survival seems to depend on the condition of the lungs at birth. In the future, correction of congenital diaphragmatic hernia in utero may be possible.
M R, Harrison, A A, de Lorimier
openaire   +2 more sources

Congenital diaphragmatic hernia

Pediatric Radiology, 2020
Congenital diaphragmatic hernia (CDH) is a potentially severe anomaly that should be referred to a fetal care center with expertise in multidisciplinary evaluation and management. The pediatric radiologist plays an important role in the evaluation of CDH, both in terms of anatomical description of the anomaly and in providing detailed prognostic ...
openaire   +2 more sources

Congenital diaphragmatic hernia

Clinical Genetics, 1980
Background—congenital diaphragmatic hernia (CDH) has a reported incidence of 1 in 2500 to 1 in 4000 live births with an estimated 30 % spontaneous abortion rate.
openaire   +3 more sources

Congenital diaphragmatic hernia

Seminars in Pediatric Surgery, 2010
Congenital diaphragmatic hernia (CDH) is a congenital anomaly consisting of a posterolateral defect in the diaphragm also known as a Bochdalek hernia. It occurs in 1 in 2000 to 3000 newborns and is associated with a variable degree of pulmonary hypoplasia (PH) and persistent pulmonary hypertension (PPH).
Keijzer, Richard, Puri, P
openaire   +3 more sources

Congenital diaphragmatic hernia

Paediatric Respiratory Reviews, 2007
The incidence of congenital diaphragmatic hernia (CDH) may be as high as 1 in 2000. Over the past two decades, antenatal diagnosis rates have increased, the pathophysiology of CDH has become better understood, and advances in clinical care, including foetal surgery, have occurred.
Paul D, Robinson, Dominic A, Fitzgerald
openaire   +2 more sources