Results 101 to 110 of about 586,499 (386)

Cryo-EM structures of herpes simplex virus type 1 portal vertex and packaged genome. [PDF]

, 2019
Herpesviruses are enveloped viruses that are prevalent in the human population and are responsible for diverse pathologies, including cold sores, birth defects and cancers.
Bi, Guo-Qiang, Dai, Xinghong, Jih, Jonathan, Liu, Yun-Tao, Zhou, Z Hong   +4 more
core  

High-Risk Corneal Graft Rejection in the Setting of Previous Corneal Herpes Simplex Virus (HSV)-1 Infection [PDF]

, 2016
Acknowledgments The authors thank M. Robertson and R. Fordyce for technical support during the duration of the study. The work performed in Aberdeen was supported by grant from Action Medical Research UK (SP4328; London, England, UK), NHS Grampian ...
Amescua, Guillermo, Forrester, John V., Hendricks, Robert L., Knickelbein, Jared E., Kuffova, Lucia, Medina, Carlos, Rowe, Alexander M., Yu, Tian   +7 more
core   +1 more source

Severe Herpes Zoster Following Varicella Vaccination in Immunocompetent Young Children

Journal of Child Neurology, 2019
Varicella vaccination is now virtually universal in North America, as well as in some European and Asian countries. Since varicella vaccine is a live attenuated virus, the virus replicates in the skin after administration and can travel via sensory ...
Amaran Moodley, J. Swanson, C. Grose, D. Bonthius   +3 more
semanticscholar   +1 more source

Synergistic Activation of Immunogenic Cell Death and the cGAS–STING Pathway by Engineered Zinc/Manganese‐Based Metal–Organic Framework Nanoplatforms for Colon Cancer Immunotherapy

Advanced Science, EarlyView.
A zinc/manganese (Zn/Mn)‐based metal‐organic framework (MOF) loaded with the STING agonist c‐di‐AMP diammonium (denoted AMP@Zn/Mn‐MOF) was developed to synergistically activate the cGAS‐STING pathway and induce immunogenic cell death. This nanoplatform reprograms the immunosuppressive tumor microenvironment, significantly enhancing anti‐PD‐L1 ...
Bingzi Zhu, Xiaodong Chen, Chang Xu, Xuehua Qian, Binglong Bai, Ji Lin, Wenhai Deng, Xiang Wang, Yuekai Cui, Shengsheng Zhao, Zuoliang Xie, Tao You, Yingpeng Huang, Xian Shen, Xufeng Lu, Weijian Sun   +15 more
wiley   +1 more source

An investigation of herpes simplex virus promoter activity compatible with latency establishment reveals VP16-independent activation of immediate-early promoters in sensory neurones [PDF]

, 2011
Herpes simplex virus (HSV) type-1 establishes lifelong latency in sensory neurones and it is widely assumed that latency is the consequence of a failure to initiate virus immediate-early (IE) gene expression. However, using a Ore reporter mouse system in
Arthur, J., Coleman, H.M., Connor, V., Efstathiou, S., Nicoll, M.P., Preston, C.M., Proenca, J.T.   +6 more
core   +1 more source

The Epidemiology of Herpes Simplex Virus Type 1 in Asia: Systematic Review, Meta-analyses, and Meta-regressions

Clinical Infectious Diseases, 2018
Background Herpes simplex virus type 1 (HSV-1) epidemiology in Asia was characterized by assessing seroprevalence levels and extent to which HSV-1 is isolated from clinically diagnosed genital ulcer disease (GUD) and genital herpes. Methods HSV-1 reports
Lara Khadr, M. Harfouche, R. Omori, G. Schwarzer, H. Chemaitelly, L. Abu-Raddad   +5 more
semanticscholar   +1 more source

Navigating an STI diagnosis: The role of social support, intergenerational learning, and transformative growth among Black women

American Journal of Community Psychology, EarlyView.
Abstract Black women face a myriad of challenges that heighten their susceptibility to sexually transmitted infections (STIs), resulting in a disproportionate impact of STIs among this population. Yet, there is a lack of research that explores how women navigate these diagnoses with resilience.
Jaleah D. Rutledge, Jasmine Abrams, Ijeoma Opara, Robin Lin Miller   +3 more
wiley   +1 more source

Coincident onset of multiple sclerosis and herpes simplex virus 1 encephalitis. a case report [PDF]

, 2017
Background: Along with vitamin D, smoking, body mass index and others, Epstein Barr virus, other herpesviruses and human endogenous retroviruses represent plausible environmental risk factors for multiple sclerosis.
Buscarinu, M. C., Ferraldeschi, Michela, Fornasiero, Arianna, Renie', Roberta, Ristori, Giovanni, Romano, Silvia, Salvetti, Marco, Trasimeni, Guido   +7 more
core   +2 more sources

Examining pathways by which socioeconomic instability in adolescence influence sexual health during emerging adulthood in an agricultural setting in California

American Journal of Community Psychology, EarlyView.
Abstract This study investigates the longitudinal impact of socioeconomic instability on teen pregnancy and sexually transmitted infection (STI) diagnosis among adolescents and young adults (AYA) living in an agricultural region and examines pathways including supportive family and social structures, decision making autonomy in romantic relationships ...
Marie C. D. Stoner, Erica N. Browne, Marissa Raymond‐Flesch, Mary Kate Shapley‐ Quinn, Nivedita L. Bhushan, Alondra Jaime‐Aguilar, Carmen Ramirez, Jessica Huante, Daisy Gallardo, Sue Napierala, Megan Comfort, Alexandra M. Minnis   +11 more
wiley   +1 more source

The complexity of dementia development and its comorbidities: The collaborative cross‐mouse population for multivarious tasks approach

Animal Models and Experimental Medicine, EarlyView.
The increasing prevalence of dementia and related neurodegenerative diseases—including Alzheimer's disease, Parkinson's disease, multiple sclerosis, and amyotrophic lateral sclerosis—poses a growing public health challenge. These conditions have traditionally been studied as isolated central nervous system disorders, but emerging evidence points to ...
Osayd Zohud, Iqbal M. Lone, Kareem Midlej, Fuad A. Iraqi   +3 more
wiley   +1 more source