Results 141 to 150 of about 13,087 (250)

Accelerate the Highly Efficient Development of mRNA Vaccines Through Advanced Computational Methods

open access: yesMedComm, Volume 7, Issue 2, February 2026.
This review explores the recent advancements in applying computational methods to optimize mRNA vaccines, with a primary focus on improvements in sequence design and delivery systems. ABSTRACT mRNA medicine is an emerging therapeutic approach that utilizes messenger RNA to synthesize functional proteins directly within target cells.
Ruichu Gu   +5 more
wiley   +1 more source

An opportunity for evidence-based care of individuals with monkeypox. [PDF]

open access: yesBMJ Evid Based Med, 2023
Donato M   +5 more
europepmc   +1 more source

Mathematical Modeling of the Role of Cytokines in Sindbis Virus Treatment of Glioblastoma

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Oncolytic viruses, specifically Sindbis virus (SINV), combined with cytokines show promising results in slowing glioma progression, but a quantitative understanding of their effects remains limited. In this study, we use an ordinary differential equation (ODE) model to examine the effect of adding cytokines to oncolytic SINV therapy.
Shriya Makam, Hana M. Dobrovolny
wiley   +1 more source

Xenotrasplante : el desafío de trasplantar con órganos de otras especies / [PDF]

open access: yes, 2000
Treball presentat a la Facultat de Veterinària de la Universitat Autònoma de Barcelona.Treball presentat a l'assignatura de Deontologia i Veterinària Legal ...
Monleón Pallarés, Marta.   +2 more
core  

Filgotinib Is an Effective and Safe Treatment Option for Difficult‐To‐Treat Ulcerative Colitis: Real‐World Evidence of the Dutch Initiative on Crohn and Colitis (ICC) Registry

open access: yesUnited European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT Background Filgotinib is a preferential Janus kinase 1 (JAK‐1) inhibitor registered for the treatment of ulcerative colitis (UC). Real‐world effectiveness of filgotinib, especially for difficult‐to‐treat (DTT, failure of ≥ 2 prior advanced therapies) patients, has been scarcely reported.
M. R. Naber   +17 more
wiley   +1 more source

[High seroprevalence of syphilis and genital herpes in migrants in transit in Chiapas, MexicoAlta soroprevalência de sífilis e herpes genital em migrantes em trânsito por Chiapas, México]. [PDF]

open access: yesRev Panam Salud Publica, 2023
Sánchez-Alemán MA   +6 more
europepmc   +1 more source

Herpes simple zosteriforme neonatal

open access: yesActas Dermo-Sifiliográficas, 2008
J. del Boz   +4 more
openaire   +1 more source

Exacerbation of Anti‐Cytomegalovirus Immunity and Mobilization of γ9δ1 T Cells During the Acute Phase of Hepatitis E Virus Infection

open access: yesMicrobiology and Immunology, Volume 70, Issue 2, Page 113-124, February 2026.
ABSTRACT HEV causes chronic infections that are detrimental to immunocompromised patients. Previous studies showed alterations of γδ T cell subsets at the acute phase of HEV infection. To assess a possible role of CMV, we have examined the frequencies and responses to CMV and HEV of blood γδ T cell subsets from control donors and acute‐phase HEV ...
Marion Retailleau   +5 more
wiley   +1 more source

A Prospective Multi‐Center Implementation Study to Improve the Diagnosis and Treatment of Benign Paroxysmal Positional Vertigo

open access: yesAcademic Emergency Medicine, Volume 33, Issue 2, February 2026.
ABSTRACT Background Benign paroxysmal positional vertigo (BPPV) is the most common cause of vertigo, yet it remains underdiagnosed and undertreated in emergency departments (EDs). Despite evidence‐based guidelines recommending bedside diagnostic maneuvers (Dix‐Hallpike and supine roll test) and canalith repositioning maneuvers (CRMs), these are ...
Robert Ohle   +11 more
wiley   +1 more source

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