Results 51 to 60 of about 23,749 (174)
This retrospective case series of acyclovir‐resistant HSV infection in pediatric patients undergoing allogeneic HSCT discusses the clinical course, associated complications, and treatment, including side effects. We propose the first algorithm for investigating and managing acyclovir‐resistant HSV infections in pediatric HSCT recipients, highlighting ...
Jenna Nunn +9 more
wiley +1 more source
HSV Encephalitis with Normal CSF — A Case Report with Review of Literature [PDF]
Herpes simplex virus encephalitis (HSVE) is one of the most potentially fatal infectious disease that should be detected as early as possible. The combination of clinical history and examination, brain computed tomography or magnetic resonance imaging ...
Gautam Rawal +3 more
doaj +1 more source
Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan +22 more
wiley +1 more source
Autoimmune encephalitis (AE) is the result of an autoimmune process that occurs as a rapidly advancing encephalopathy. Autoimmune encephalitis was commonly linked to herpes simplex virus 1 (HSV-1) as the most frequently identified virus.
Shihui Sun +6 more
doaj +1 more source
EGR Proteins Mediate Interferon‐Independent Anti‐HSV‐1 Responses Through Viral and Host Targets
Early antiviral responses are typically mediated by interferons. However, during HSV‐1 infection, host early growth response (Egr) genes, which are not interferon‐stimulated genes, are quickly induced by viral protein ICP0. EGR proteins, in turn, suppress viral lytic infection by activating viral latency‐associated (LAT) and host immune regulatory ...
Shuaishuai Wang +4 more
wiley +1 more source
A Fatal Case of Herpes Simplex Encephalitis with Two False-Negative Polymerase Chain Reactions
An 88-year-old man presented with a 1-month history of altered mental status and seizures. His electrographic and imaging findings were suggestive of herpes simplex encephalitis (HSE), for which he was empirically treated with acyclovir. He underwent two
Aldo A. Mendez +5 more
doaj +1 more source
Can we refute a role for infections in Alzheimer's disease pathogenesis?
Abstract While a growing body of literature suggests a role for infections in Alzheimer's disease (AD), microbial contributions to AD remains a contentious topic, in part due to challenges in reconciling the positive evidence with studies reporting null findings.
Zena K. Chatila +6 more
wiley +1 more source
Eczema Monkeypoxicum Following Sexual Transmission Treated With Tecovirimat
Capsule summary Mpox is a zoonotic infection that may present severe dissemination in patients with pre‐existing dermatoses. We report a 30‐year‐old man with active atopic dermatitis who developed extensive, sexually transmitted mpox with widespread cutaneous involvement consistent with eczema monkeypoxicum.
Andrés Vidal González +6 more
wiley +1 more source
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Katharina A. Kälber +3 more
wiley +1 more source
This review focuses on the clinical features, molecular mechanisms, treatment methods, and preventive measures of the VZV, with the aim of providing a theoretical basis for the development of new treatment and prevention methods for HZ. ABSTRACT Varicella zoster virus (VZV) is a ubiquitous human herpesvirus that establishes lifelong latency and causes ...
Lei Peng +8 more
wiley +1 more source

