Results 111 to 120 of about 233,864 (300)
Gain‐of‐function enhancers optimize CAR‐NK cell‐based anti‐cancer immunotherapy
Immunology &Cell Biology, EarlyView.Schematic overview of the two‐stage screening approach used to identify NK cell fitness genes. (A) CRISPRa mechanism, showing dCas9‐VP64‐mediated upregulation of target genes. (B) Whole‐genome CRISPRa screening in HER2‐CAR‐NK92 cells transduced with a CRISPR sgRNA library and transferred into mice bearing HT29 tumours, followed by tumour collection and
Emma Wong +1 more
wiley +1 more source
Glioblastoma mimicking anti‐NMDA receptor encephalitis: a case series
Internal Medicine Journal, EarlyView.Abstract Anti‐N‐methyl‐D‐aspartate receptor (anti‐NMDAR) GluN1‐IgG antibodies are the hallmark of anti‐NMDAR encephalitis, a common type of autoimmune encephalitis. We describe two men with seizures and asymmetric, mass‐like temporal lesions initially treated as anti‐NMDAR encephalitis: Case 1 had serum and cerebrospinal fluid (CSF) NMDAR‐IgG ...
Sophie Chatterton +7 more
wiley +1 more source
Optimal Control Strategy on the Transmission Dynamics of Herpes Simplex Virus-II (HSV-II)
, 2021 Eshetu Gurmu +2 more
openalex +1 more source
Tissue Resident Memory Cells: Friend or Foe?
Immunology, EarlyView.Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude +2 more
wiley +1 more source
Prevalence and Incidence of Herpes Simplex Virus Type 2 Infection among Male Zimbabwean Factory Workers [PDF]
, 1999 William McFarland +8 more
openalex +1 more source
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Katharina A. Kälber +3 more
wiley +1 more source
Gingival and Periodontal Diseases and Conditions in Children and Adolescents: Consensus Report
Journal of Clinical Periodontology, EarlyView.ABSTRACT Background The objectives of this Focused Workshop were to update the epidemiology, aetiology, risk factors, diagnosis and management of gingival and periodontal diseases and conditions in children and adolescents, and to explore the applicability of the 2018 Classification in children and adolescents.
Iain Chapple +30 more
wiley +1 more source
Herpes simplex virus-based nerve targeting gene therapy in pain management
, 2014 Darren Wolfe +3 more
openalex +2 more sources