ABSTRACT Precise genome editing has transformed plant biology and crop improvement by enabling targeted modification of endogenous loci. Beyond gene knockout and base editing, the site‐specific insertion of exogenous DNA, particularly large DNA fragments, has become a central goal for engineering complex traits, reconstructing metabolic pathways and ...
Fengfeng Zhang +6 more
wiley +1 more source
Genome sequence of seven human herpes simplex virus 2 (HSV2) clinical isolates from Finland. [PDF]
Bowen CD +5 more
europepmc +1 more source
Immune dysregulation in mania: A proof‐of‐concept platelet proteomics study
Aims Bipolar disorder (BD) is a major psychiatric condition with a multifaceted and largely unknown pathophysiology. Mania, the defining feature of BD, remains underinvestigated. Proteomics offers a powerful, data‐driven, unbiased approach to uncover biological alterations.
Paola Magioncalda +6 more
wiley +1 more source
Herpes simplex virus 2 and dementia risk: a systematic review and meta-analysis. [PDF]
Hunt CJ +13 more
europepmc +1 more source
Herpes Simplex Virus (HSV)-2 Candidate Vaccine Virus Deleted in Glycoprotein D (ΔgD-2) Elicits High-Titer Immunoglobulin (Ig)G2 Antibodies With Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) Activity, Protects Mice From Skin and Vaginal Challenge With Clinical Isolates of HSV-1 and HSV-2, and Prevents the Establishment of Latency [PDF]
Betsy C. Herold +6 more
openalex +1 more source
Low frequency variants can predetermine antiviral drug resistance development in herpes simplex virus type 1. [PDF]
Jaki L +7 more
europepmc +1 more source
T cells and the regulation of herpes simplex virus latency and reactivation
Anthony A. Nash, Nash, A A
core +1 more source
ABSTRACT Background COVID‐19 has had major global health impacts, yet reported morbidity and mortality have been lower in Africa despite serological evidence of widespread infection. Malaria has been proposed as a potential modifier of susceptibility to and outcomes of SARS‐CoV‐2 infection.
Ludoviko Zirimenya +22 more
wiley +1 more source

