Results 141 to 150 of about 36,154,205 (252)
The Significance of cGAS‐STING Signaling in Response to Oncogenic Viruses
ABSTRACT The cyclic GMP‐AMP synthase (cGAS)‐stimulator of interferon genes (STING) signaling pathway, as a key DNA sensor, plays a significant role in the regulation of innate immune responses. This pathway can be activated by sensing abnormal DNA, and is of great significance for resisting the invasion of pathogenic microorganisms and maintaining ...
Limei Guo +4 more
wiley +1 more source
Beyond the Rash: Simultaneous Bilateral Facial Nerve Palsy Following Childhood Varicella Infection
ABSTRACT Bilateral facial nerve palsy is a rare neurological condition in children and is infrequently associated with primary Varicella (chickenpox) infection. We report the case of a 10‐year‐old previously healthy girl who developed simultaneous bilateral lower motor neuron facial weakness 3 weeks after a self‐limiting varicella infection.
Mohamed Sheikh Hassan +7 more
wiley +1 more source
Chapter 19 Human herpesvirus-6 and HIV-1 infection
Publisher Summary Since the discovery of HHV-6, attempts have been made to determine what role it plays in the progressive destruction of the immune system by the HIV-1 virus. Studies have been equally disappointing in helping to define the role of HHV-6 in HIV-1 infections. Studies have shown that HHV-6 and HIV-1 could infect the same cell.
openaire +1 more source
リンパ増殖性疾患とHuman herpesvirus 6 (HHV-6)の関連性のPCR法による検討(第1報)
Human herpesvirus 6 (HHV-6)は1986年に新たに発見されたウイルスであり様々な疾患との関連性が示唆されている。HHV-6とリンパ増殖性疾患との関連性を検討するために、このウイルスDNAに特異的なプライマーを作製し、それを用いたPCR法で、患者より採取した末梢血およびリンパ組織中のHHV-6ゲノムの検出を行った。 8名の健常人、40例のリンパ増殖性疾患、1例の慢性骨髄性白血病について検討したが、今回施行した49検体では、HHV-6は検出されず、HHV ...
サダ, エイジ +15 more
core +1 more source
Manufacturing and clinical applications of non‐CAR‐T immune effector cells
Transfusion, EarlyView.
Thane Kubik +2 more
wiley +1 more source
Next‐Generation Sequencing Methods for Sensitive Hepatitis B Viral Genome Analysis: A European Study
ABSTRACT This multicentre study investigated the utility of next‐generation sequencing (NGS) to detect and generate hepatitis B virus (HBV) genomes in samples of low viral load (from 0.2 to 6207 IU/mL). 23 HBV DNA‐positive plasma samples of genotypes A‐E and one HBV‐negative control sample were assayed blindly via 9 established NGS methods from 6 ...
Michael X. Fu +28 more
wiley +1 more source
Role of the human beta-herpesviruses in organ allograft rejection following transplantation. [PDF]
In previous prospective studies conducted in our department, PCR was used to detect the three ({dollar}-herpesviruses, human cytomegalovirus (HCMV), and human herpesviruses 6 and 7 (HHV-6 and HHV-7) in the blood of solid organ transplant patients.
Li, Y.T., Li, Yingting
core
Human Cytomegalovirus Genetic Diversity, Clinical Relevance, and Emerging Insights
ABSTRACT Human cytomegalovirus (HCMV) is a globally prevalent virus that poses a significant public health concern, especially for newborns and immunocompromised patients, causing a wide range of infections. Clinical outcomes associated with HCMV infection include congenital disease, graft rejection in transplant recipients, and life‐threatening ...
Hajar Y. AlQahtani +2 more
wiley +1 more source

