Results 151 to 160 of about 1,291,105 (289)

A guide to heat shock factors as multifunctional transcriptional regulators

The FEBS Journal, EarlyView.
The heat shock factors (HSFs) are evolutionarily conserved transcription factors best known as regulators of molecular chaperone genes in response to heat shock and other protein‐damaging stresses. Vertebrate HSFs, HSF1‐5, HSFX, and HSFY, are implicated in various physiological and pathological processes, including organismal development and cancer ...
Hendrik S. E. Hästbacka, Alejandro J. Da Silva, Lea Sistonen, Eva Henriksson   +3 more
wiley   +1 more source

Mycobacterium avium Subsp. paratuberculosis and Human Endogenous Retrovirus in Italian Patients With Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS)

Immunology, EarlyView.
Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), is a recognised gastrointestinal disorder. Mycobacterium avium subspecies paratuberculosis (MAP) is implicated in IBD pathogenesis. Persistent exposure and active infections by MAP may contribute to the unsilencing of human endogenous retroviruses (HERV ...
Stefano Ruberto, Alfredo Santovito, Gian P. Caviglia, Marta Noli, Davide Cossu, Davide G. Ribaldone, Demis Pitoni, Simona Frara, Elisa Tribocco, Chiara Rosso, Marta Guriglia, Ilaria Cossu, Pier A. Tovo, Massimiliano Bergallo, Leonardo A. Sechi   +14 more
wiley   +1 more source

Herpesvirus Simplex Virus‐1 Exploits Inflammation to Infect Periodontal Stem Cells and Disrupt Lineage Commitment

Journal of Periodontal Research, EarlyView.
HSV‐1 infects oral mesenchymal stem cells both in vitro and in vivo to dysregulate their lineage commitment. An inflamed gingival environment increases susceptibility to HSV‐1 infection, which further elevates proinflammatory cytokine levels and exacerbates alveolar bone loss.
Araceli Valverde, Raza Ali Naqvi, Yinghua Chen, Alireza Moshaverinia, Anne George, Deepak Shukla, Gloria Martinez, Gabriella Chapa, Salvador Nares, Afsar R. Naqvi   +9 more
wiley   +1 more source

A rare histologic variant of Kaposi’s sarcoma

Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2023
An 80-year-old male presented with a 3-year history of progressive violaceous and edematous plaques on both hands. The remaining physical examination was unremarkable and systemic symptoms were absent.
Ana S. Pereira, Carolina Figueiredo, Rebeca Calado, José C. Cardoso   +3 more
doaj  

Enhancing melatonin biosynthesis in crops through synthetic genetic circuits: A strategy for nutritional fortification in soybean and stress resistance in cotton

Plant Biotechnology Journal, EarlyView.
Summary Melatonin has gained considerable prominence in the treatment of insomnia that significantly impacts one‐third of the global population. The production of melatonin remains challenging due to limitations in current methods. Thus, there is an urgent need for developing more efficient and innovative production techniques.
Yue Shi, Zegang Han, Wanying Zhang, Lu He, Zhuolin Shi, Xiaowei Ma, Ji Zhou, Zhanfeng Si, Yan Hu, Tianzhen Zhang   +9 more
wiley   +1 more source

Characterization of a continuous feline mammary epithelial cell line susceptible to feline epitheliotropic viruses. [PDF]

, 2009
Mucosal epithelial cells are the primary targets for many common viral pathogens of cats. Viral infection of epithelia can damage or disrupt the epithelial barrier that protects underlying tissues.
Heymer, Anna, Liu, Hongwei, Millon, Lee, Ossiboff, Robert J, Parker, John SL, Pesavento, Patricia, Stucker, Karla M, van der List, Deborah, Wood, Jason   +8 more
core  

Photodynamic therapy of cancer‐associated infections

Photochemistry and Photobiology, EarlyView.
Pathogens can be involved in tumor initiation, promotion and progression through different mechanisms, and their treatment can prevent new cancer cases, improve outcomes, and revert poor‐prognostic phenotypes. Photodynamic therapy (PDT) successfully treats different types of cancers and infections, and, therefore, has a unique potential to address ...
Giulia Kassab, Juan Chen, Gang Zheng
wiley   +1 more source

The relationship between maternal periodontitis and congenital cytomegalovirus: A hypothetical model and therapeutic implications

Periodontology 2000, EarlyView.
Abstract Background The primary goal of periodontology is to prevent tooth loss and reduce the risk of focal infections. Periodontitis lesions can harbor hundreds of thousands of active cytomegaloviruses (virions), which can easily enter the systemic circulation and potentially infect the fetus of a mother with compromised immunity.
Jørgen Slots
wiley   +1 more source

Cyprinid Herpesvirus 3 Il10 Inhibits Inflammatory Activities of Carp Macrophages and Promotes Proliferation of Igm+ B Cells and Memory T Cells in a Manner Similar to Carp Il10

Journal of Immunology, 2015
M. C. Piazzon, Annelieke S Wentzel, Edwin J. Tijhaar, K. Rakus, A. Vanderplasschen, G. Wiegertjes, M. Forlenza   +6 more
semanticscholar   +1 more source

Current Practice Patterns and Educational Needs of the ESCMID Study Group for Infections in Compromised Hots

Transplant Infectious Disease, EarlyView.
The ESGICH survey highlights variability in training and support for Immunocompromised Host Infectious Diseases (ICH‐ID). Respondents expressed strong interest in structured education, research collaboration, and certification, underscoring the need for targeted initiatives to strengthen expertise, improve patient care, and define ICH‐ID as a ...
Maddalena Giannella, Daniele Riccucci, Renato Pascale, Elisa Cordero, Nicolas J. Mueller, Monica Slavin, Michael Ison, the ECCMID study groups on Invasive Fungal Infection and Infection in Immunocompromised Hosts   +7 more
wiley   +1 more source