Results 91 to 100 of about 94,635 (191)

Frequency and Characterization of Local Ocular Toxicity in Cats Treated With Topical Ophthalmic Cidofovir for Presumptive Feline Herpesvirus‐1 Infection

Veterinary Ophthalmology, EarlyView.
ABSTRACT Objective To determine the frequency and clinical characteristics of local ocular adverse reactions to topical ophthalmic cidofovir administration in cats with presumptive feline herpesvirus‐1 (FHV‐1) keratoconjunctivitis. Animal Studied In total, 140 cats treated with cidofovir.
Eric C. Ledbetter, Amy J. Morgan
wiley   +1 more source

Mosaic arthroplasty in equine stifle and fetlock joints: A retrospective study of 31 cases between 1998 and 2023

Veterinary Surgery, EarlyView.
Abstract Objective To evaluate the clinical application of equine mosaic arthroplasty for joint surface repair, including outcomes and complications. Study design Retrospective clinical study. Animals A total of 31 horses diagnosed with subchondral bone cysts (SBCs) in the femoral condyle (22/31), distal metacarpus (7/31), or metatarsus (2/31 ...
Zsófia Pál, Pál Tuska, Gábor Vásárhelyi, László Hangody, Mark Hurtig, András D. Kaposi, Gábor Bodó   +6 more
wiley   +1 more source

Efficacy of High‐Dose Intravenous Anakinra in Pediatric TAFRO Syndrome: Report of Two Cases and Literature Review

Pediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT TAFRO (thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly) syndrome is a rare, life‐threatening inflammatory condition linked to infections, neoplasms, and idiopathic multicentric Castleman disease. Interleukin (IL)‐6 inhibitors are the primary treatment, but refractory cases require alternatives. This
Serena Palmeri, Jacopo Ferro, Valentina Natoli, Caterina Matucci‐Cerinic, Riccardo Papa, Silvia Rosina, Stefania Sorrentino, Stefano Volpi, Valerio Gaetano Vellone, Marco Gattorno, Roberta Caorsi   +10 more
wiley   +1 more source

Human herpesvirus type 6 in patients with systemic lupus erythematosus

Iranian Journal of Microbiology
Background and Objectives: Infectious agents are considered one of the possible etiological factors of systemic lupus erythematosus (SLE). It has been suggested that human herpesvirus type 6 (HHV-6) may trigger autoimmune disorders, but few studies have
Mohammad Shayestehpour, Elnaz Vatani, Batool Zamani, Ahmad Piroozmand, Shaghayegh Yazdani, Kamal Esalatmanesh, Zahrasadat Fateminasab   +6 more
doaj   +1 more source

Torque teno virus as a marker of immune status in immunocompromised patients: A systematic review

European Journal of Clinical Investigation, Volume 55, Issue 8, August 2025.
Abstract Background Torque teno virus (TTV) is not known to cause disease in humans; however, chronic inflammatory conditions and immunosuppression states can favour TTV replication. This study aimed to verify the effectiveness of TTV as an immune biomarker.
Janaina B. Medina, Fábio França Vieira e Silva, Rafael Antônio Velôso Caixeta, Bruna de Oliveira Rech, Alba Perez‐Jardón, María Elena Padín‐Iruegas, Mario Pérez‐Sayáns, Paulo Henrique Braz‐Silva, Karem L. Ortega   +8 more
wiley   +1 more source

Human sporadic breast carcinoma histotypes driven by the Human Betaretrovirus homologous to Mouse Mammary Tumor Virus

International Journal of Cancer, Volume 157, Issue 2, Page 371-383, 15 July 2025.
What's new? While estrogens, obesity, and alcohol are recognized risk factors for breast cancer, a viral hypothesis has been suggested based on the murine model of Mouse Mammary Tumor Virus (MMTV)‐induced mammary tumors. This study analyzed sequences of the human homolog of MMTV across human breast carcinoma histotypes, detecting the virus in all types
Prospero Civita, Chiara Maria Mazzanti, Francesca Lessi, Caterina Marchiò, Cristian Scatena, Michele Menicagli, Matteo Ghilli, Manuela Roncella, Antonio Giuseppe Naccarato, Anna Sapino, Jacob Hochman, Mauro Pistello, Generoso Bevilacqua   +12 more
wiley   +1 more source

Structure and Antigenicity of Kaposi's Sarcoma‐Associated Herpesvirus Glycoprotein B

Advanced Science, Volume 12, Issue 27, July 17, 2025.
Kaposi's sarcoma‐associated herpesvirus (KSHV) causes severe cancers without effective treatments. This study presents an atomic model of KSHV's critical infection protein, gB, revealing a unique structure shared with related herpesviruses like Epstein‐Barr virus (EBV). The structural similarity highlights vulnerable targets for antibodies, guiding the
Xin‐Yan Fang, Cong Sun, Chu Xie, Bing‐Zhen Cheng, Zheng‐Zhou Lu, Ge‐Xin Zhao, Sen‐Fang Sui, Mu‐Sheng Zeng, Zheng Liu   +8 more
wiley   +1 more source

Kaposi Sarcoma‐Associated Herpesvirus Sequencing in People Living With HIV in the Southern United States Reveals Subtype Diversity and Multiple Infections

Journal of Medical Virology, Volume 97, Issue 7, July 2025.
ABSTRACT Kaposi sarcoma‐associated herpesvirus (KSHV) is the causative agent of Kaposi's sarcoma and lymphoproliferative diseases collectively identified as KSHV‐associated diseases (KAD). While KAD incidence has decreased across the United States, regional and population‐based variability exists, with higher rates in southern states. To understand the
Vickie A. Marshall, Sheena M. Knights, Elena M. Cornejo Castro, Nazzarena Labo, Isabella Liu, Wendell J. Miley, Kyle N. Moore, Charles A. Goodman, Christine M. Fennessey, Brandon F. Keele, Susana M. Lazarte, Elizabeth Y. Chiao, Ank E. Nijhawan, Denise Whitby   +13 more
wiley   +1 more source

KSHV vIL6 Inhibits Functional B Cell Maturation During De Novo Infection

Journal of Medical Virology, Volume 97, Issue 7, July 2025.
ABSTRACT Despite causative links to lymphoproliferative disorders, little is known about early events governing KSHV infection in B lymphocytes. IL‐6 signaling plays a critical role in KSHV‐mediated disease, with human IL‐6 (hIL6) levels correlating with viral load and disease progression.
Wajd Zakir, Jessica M. Osborn, Jennifer E. Totonchy   +2 more
wiley   +1 more source

Endoplasmic Reticulum Stress in Cancer

MedComm, Volume 6, Issue 7, July 2025.
Persistent ER stress in tumors activates UPR sensors (IRE1α, PERK, ATF6), driving cancer proliferation, metastasis, immune evasion, and drug resistance. This review explores UPR‐mediated signaling crosstalk, angiogenesis, and therapeutic targeting to develop safer anticancer strategies.
Ruixin Zhou, Wenlong Wang, Baizhao Li, Zhu Li, Juan Huang, Xinying Li   +5 more
wiley   +1 more source