An alphaherpesvirus exploits antimicrobial beta-defensins to initiate respiratory tract infection [PDF]
beta-Defensins protect the respiratory tract against the myriad of microbial pathogens entering the airways with each breath. However, this potentially hostile environment is known to serve as a portal of entry for herpesviruses.
Boyen, Filip +8 more
core +2 more sources
The zebrafish xenograft platform-A novel tool for modeling KSHV-associated diseases [PDF]
Kaposi\u27s sarcoma associated-herpesvirus (KSHV, also known as human herpesvirus-8) is a gammaherpesvirus that establishes life-long infection in human B lymphocytes.
Berman, Jason N +12 more
core +2 more sources
Risk factors for high anti-HHV-8 antibody titers (≥1:51,200) in black, HIV-1 negative South African cancer patients: a case control study [PDF]
Background: Infection with human herpesvirus 8 (HHV-8) is the necessary causal agent in the development of Kaposi's sarcoma (KS). Infection with HIV-1, male gender and older age all increase risk for KS.
BM Friedman +51 more
core +2 more sources
Structure of the herpes-simplex virus portal-vertex [PDF]
Herpesviruses include many important human pathogens such as herpes simplex virus, cytomegalovirus, varicella-zoster virus, and the oncogenic Epstein–Barr virus and Kaposi sarcoma–associated herpesvirus.
Bhella, David +3 more
core +2 more sources
Glass eels and viruses – a lesson learnt from stocking the eastern German Baltic Sea coast
Abstract Concerns about Anguillid herpesvirus 1 (AngHV‐1) in European eels, especially due to stocking measures, is increasingly coming into focus and raises questions regarding disease monitoring and prevention. In the past, stocking of AngHV‐1‐positive eels into waters assumed AngHV‐1‐free has led to a rapid increase of infected eels in the wild. For
Laura Kullmann +3 more
wiley +1 more source
Kaposi's sarcoma-associated herpesvirus oncoprotein K13 protects against B cell receptor induced growth arrest and apoptosis through NF-κB activation [PDF]
Kaposi's sarcoma-associated herpesvirus (KSHV) has been linked to the development of Kaposi's sarcoma, primary effusion lymphoma and multicentric Castleman's disease (MCD). We have characterized the role of KSHV-encoded viral FLICE inhibitory protein K13
Ahmad +53 more
core +1 more source
Posttransplant lymphoproliferative disorders in neuronal xenotransplanted macaques [PDF]
Posttransplant lymphoproliferative disorders (PTLDs) are a heterogeneous group of lymphoid proliferations that occur in the setting of depressed T-cell function due to immunosuppressive therapy used following solid organ transplantation, hematopoietic ...
Aron Badin, R. +12 more
core +1 more source
Estudio genómico de cepas argentinas de Herpesvirus equino 1 [PDF]
La infección por Herpesvirus equino 1 (EHV-1) tiene un significativo impacto económico en la producción equina mundial al causar abortos, enfermedad respiratoria, muertes perinatales y desórdenes neurológicos.
Eöry, Matías Leonel +5 more
core +2 more sources
Short communication: NKG2C+ NK cells contribute to increases in CD16+CD56- cells in HIV type 1+ individuals with high plasma viral load. [PDF]
Chronic HIV-1 infection results in the expansion of both NKG2C+ and CD16+CD56- human natural killer cells. NKG2C+ cells proliferate in response to human cytomegalovirus (HCMV) and expansion of the dysfunctional CD56-CD16+ natural killer (NK) cells is ...
Bower, Mark +5 more
core +1 more source
Human herpesvirus 6 and epilepsy
AbstractWe investigated the association between human herpesvirus 6 (HHV‐6) and mesial temporal sclerosis (MTS) in 87 patients who had surgery for drug‐resistant epilepsy. Fifty‐four had MTS, 22 focal cortical dysplasia (FCD), four tumors, three vascular malformations, and three a history of encephalitis.
William H. Theodore +7 more
openaire +3 more sources

