Results 71 to 80 of about 214,608 (288)

1‐Azabicyclo[1.1.0]butanes (ABBs) on the Map: Mechanistic Pathways for Catalytic Ring Opening and Functionalizations

Angewandte Chemie, EarlyView.
Catalytic strain‐release ring opening and functionalizations of 1‐azabicyclo[1.1.0]butanes (ABBs) represent a promising strategy for accessing diverse azetidine products. These transformations proceed via polar pathways, radical pathways, and hybrid mechanisms that combine both.
James Shao‐Jiun Yang, Hsuan‐Hung Liao   +1 more
wiley   +2 more sources

Push–pull fluorophores based on NHS esters of bithiophene for labelling of biomolecules containing primary amines

Royal Society Open Science
Fluorescent labelling is a versatile tool to visualize biomolecules containing primary amines in their cellular environment, allowing the study of their function or interactions.
Mariana Barros, Pau Arroyo, Jose A. Sáez, Salvador Gil, Margarita Parra, Susana P. G. Costa, M. Manuela M. Raposo, Pablo Gaviña   +7 more
doaj   +1 more source

Opportunities and challenges for direct C–H functionalization of piperazines

Beilstein Journal of Organic Chemistry, 2016
Piperazine ranks within the top three most utilized N-heterocyclic moieties in FDA-approved small-molecule pharmaceuticals. Herein we summarize the current synthetic methods available to perform C–H functionalization on piperazines in order to lend ...
Zhishi Ye, Kristen E. Gettys, Mingji Dai
doaj   +1 more source

Microwave Assisted Synthesis of N-Arylheterocyclic Substituted-4-aminoquinazoline Derivatives

Molecules, 2006
A simple, efficient, and general method has been developed for the synthesis of various N-aryl heterocylic substituted-4-aminoquinazoline compounds from 4-chloro- quinazoline and aryl heterocyclic amines under microwave irradiation using 2-propanol as ...
Ping Lu, Linhong Jin, Deyu Hu, Wei Xue, Baoan Song, Song Yang, Gang Liu   +6 more
doaj   +1 more source

Two food-borne heterocyclic amines: Metabolism and DNA adduct formation of amino-alpha-carbolines

, 2005
The amino-alpha-carbolines 2-amino-9H-pyrido[2,3-b]indole (A alpha C) and 2-amino-3-methyl-9H-pyrido-[2,3-b]indole (MeA alpha C) are two mutagenic and carcinogenic heterocyclic amines formed during ordinary cooking.
Frederiksen, Hanne
core   +1 more source

N-Heterocyclic carbene copper(I) catalysed N-methylation of amines using CO2 [PDF]

, 2015
The authors gratefully acknowledge the Royal Society (University Research Fellowship to C.S.J.C.), the EPSRC (DTG011 EP/J500549/1) and the King Abdullah University of Science and Technology for funding, and the EPSRC National Mass Spectrometry Service ...
Cazin, Catherine, Cazin C. S. J., Santoro O., Cavallo L., Cavallo, Luigi, Minenkov Y., Cazin, Catherine S.J., Santoro, Orlando, Cazin, Catherine S. J., Lazreg, Faima, Lazreg F., Minenkov, Yury   +11 more
core   +1 more source

Novel Synthesis of 8-Deaza-5,6,7,8-tetrahydroaminopterin Analogues via an Aziridine Intermediate

Molecules, 2012
An efficient method for the construction of the tetrahydrofolate skeleton is described. Starting from pterin analogues and aromatic amines, 8-deaza-5,6,7,8-tetrahydroaminopterin derivatives and the heterocyclic benzoyl isosteres were synthesized via a ...
Zhili Zhang, Chao Li, Ying Guo, Junyi Liu, Xiaowei Wang, Chao Tian, Shouxin Zhou   +6 more
doaj   +1 more source

Dietary exposure to heterocyclic amines in high-temperature cooked meat and fish in Malaysia [PDF]

, 2010
The intake of heterocyclic amines is influenced by the amount and type of meat and fish inges ted, frequency of consumption, cooking methods, cooking temperature, and duration of cooking.
P. Hajeb, SJ. Ang, M.H.A. Jahurul, S. Jinap, I.S.M. Zaidul, A. Abdul-Hamid, H.N. Lioe   +6 more
core  

Inhibitory effect of tarragon usage on the formation of heterocyclic aromatic amines in meatball preparation

, 2020
Heterocyclic aromatic amines are carcinogenic and/or mutagenic compounds formed during cooking ofproteinaceous foods such as beef, chicken, and fish. Therefore, it is needed to reduce their amounts in cookedmeat.
Bulan, Revşan, Aoudeh, Eyad, Öz, Fatih
core  

One‐Pot Biphasic Photocatalytic CO2‐to‐Carbonylation Cascades

Angewandte Chemie, EarlyView.
Bioinspired biphasic compartmentalization enables one‐pot cascades where photocatalytic CO2 reduction generates CO for carbonylative cross‐couplings to synthesize complex organic products, including a pharmaceutical. ABSTRACT Photosynthesis compartmentalizes reactions across the thylakoid membrane in vivo to upcycle CO2 into complex chemicals that are ...
Sampurna Mitra, David M. Vahey, Shannon A. Bonke, Erwin Reisner   +3 more
wiley   +1 more source