Results 111 to 120 of about 38,755 (208)

The Role of Long Noncoding RNAs in Modulation of Stress Granules in Cancer

Journal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.
ABSTRACT Stress granules are dynamic cellular structures that arise in response to stress. They play an important role in cancer cell survival by modulating multiple stress responses. Long noncoding RNAs (lncRNAs) have been identified as crucial regulators of stress granule (SG) dynamics, influencing cancer development and treatment resistance. LncRNAs
Nazlı Şevval Menemenli, Bünyamin Akgül   +1 more
wiley   +1 more source

From the Proteome to Therapeutics: A Multi‐Database Approach to Drug Discovery in Periodontitis—An Exploratory Pilot Study

Journal of Clinical Periodontology, Volume 53, Issue 7, Page 990-1004, July 2026.
ABSTRACT Introduction This explanatory pilot study presents a workflow to identify approved drugs, which could be repurposed for periodontitis therapy using salivary proteomics combined with drug‐target database screening. Methods Proteomic analyses of saliva using LC–MS/MS were conducted in two independent settings: a cohort (sub‐study I, N = 187) and
Taisir Bozo, Annette Murr, Birte Holtfreter, Sebastian‐Edgar Baumeister, Peter Meisel, Uwe Völker, Werner Weitschies, Henry Völzke, Philipp Kanzow, Elke Hammer, Manuela Gesell Salazar, Thomas Kocher   +11 more
wiley   +1 more source

Single‐nuclei RNA sequencing reveals heterogeneity within developing GnRH3 neurons in zebrafish

Journal of Neuroendocrinology, Volume 38, Issue 7, July 2026.
Abstract Gonadotropin‐releasing hormone (GnRH) is a central regulator of vertebrate reproduction regulating pituitary gonadotropins. In zebrafish, GnRH3 serves as the hypophysiotropic isoform. Its neurons develop by migrating from the nasal placode to the hypothalamus, forming several distinct subpopulations along the migratory path.
Yalong Sun, Matan Golan, Yonathan Zohar, Xiaoxuan Fan, Nilli Zmora   +4 more
wiley   +1 more source

Multiomics Profiling During Autoimmune Demyelination Highlights a Complex Regulatory Role for Ataxin‐1 in B Cells

Annals of the New York Academy of Sciences, Volume 1561, Issue 1, July 2026.
Ataxin‐1 has been recently implicated in B cell regulation in the context of multiple sclerosis pathology. In this study, we used a multiomics pipeline to profile the B cell transcriptome, epigenome, and proteome in response to encephalitogenic challenges.
Jonathan J. Carver, Rachael R. Denbrock, Kristy M. Lau, Tonya N. Zeczycki, Changhong Yin, Weihua Huang, Alessandro Didonna   +6 more
wiley   +1 more source

Inhibition of RAN attenuates influenza a virus replication and nucleoprotein nuclear export [PDF]

Nuclear export of the viral ribonucleoprotein (vRNP) is a critical step in the influenza A virus (IAV) life cycle and may be an effective target for the development of anti-IAV drugs.
Xianfeng Hui, Ya Zhao, Chuxing Cheng, Lei Cao, Haiying Mao, Meilin Jin, Xian Lin, Ting Wang, Ting Xu, Yumei Zhang, Kun Huang, Xiaomei Sun, Lianzhong Zhao, Ziwei She, Yaqin Li   +14 more
core   +1 more source

Alphavirus infection triggers selective cytoplasmic translocation of nuclear RBPs with moonlighting antiviral roles [PDF]

RNA is a central molecule for viruses; however, the interactions that viral RNA (vRNA) establishes with the host cell is only starting to be elucidated.
Demyanenko, Yana, Orton, Richard J., Castello, Alfredo, Mohammed, Shabaz, Davis, Ilan, Järvelin, Aino I, Järvelin, Aino, de Laurent, Zaydah R., Hannan, Maximilian, Moore, Samantha, Orton, Richard J, Kamel, Wael, Noerenberg, Marko, Merits, Andres, Ruscica, Vincenzo, Madhusudhan, Meghana, de Laurent, Zaydah R, Kitano, Eduardo, Garcia-Moreno, Manuel, Embarc-Buh, Azman, Iselin, Louisa   +20 more
core   +1 more source

Heterogeneous nuclear ribonucleoprotein complexes and proteins in Drosophila melanogaster

Molecular and Cellular Biology, 1992
G. Raychaudhuri, S. Haynes, A. Beyer
semanticscholar   +1 more source

The role of polyhomeotic in polycomb group-mediated regulation of the tumour suppressor P16INK4A [PDF]

, 2010
The INK4A tumour suppressor gene is negatively regulated by the Polycomb Group (PcG) complexes, which plays an important role in stem cell- and cancer biology.
de Breed, L.A.
core  

The Drosophila Hrb87F gene encodes a new member of the A and B hnRNP protein group

Nucleic Acids Res., 1991
Susan R. Haynes, Diana Johnson, G. Raychaudhuri, A. Beyer   +3 more
semanticscholar   +1 more source

HNRNPR Regulates the Expression of Classical and Nonclassical MHC Class I Proteins

Journal of Immunology, 2016
A. Reches, D. Nachmani, O. Berhani, Alexandra Duev-Cohen, Dorin Shreibman, Y. Ophir, B. Seliger, O. Mandelboim   +7 more
semanticscholar   +1 more source