Results 91 to 100 of about 1,248,808 (269)
Quantum lock-in measurement of weak alternating signals
Quantum FrontiersThe detection of weak time-dependent alternating signals in a strongly noisy background is an important problem in physics and a critical task in metrology. Quantum lock-in amplifier can extract alternating signals within extreme noises by using suitable
Min Zhuang +3 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
IEEE Open Journal of Antennas and PropagationIn this paper, a low-cost compact decoupled bandwidth enhancement technique is proposed to address the high mutual coupling issue between wideband closely-spaced multiple-input and multiple-out (MIMO) patch antennas.
Lina Ma +4 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Monolayer Chiral Metasurface for Generation of Arbitrary Cylindrical Vector Beams
PhotonicsThe cylindrical vector beam (CVB) has been widely studied and applied in recent years. However, many CVB generation methods suffer from complex systems, and large-size devices are required. Here, we propose a monolayer chiral metasurface composed of spin-
Qian Chen +6 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Structureless excitation and manipulation of dynamic holographic plasmonic slides
Nature CommunicationsSurface plasmons are bound modes at metal–dielectric interfaces and enable a wide range of applications. However, holographic plasmonic fields are usually realized with complex nanostructures, introducing diffraction background and limiting flexibility ...
Yuquan Zhang +8 more
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A Point Cloud Improvement Method for High-Resolution 4D mmWave Radar Imagery
Remote SensingTo meet the requirement of autonomous driving development, high-quality point cloud generation of the environment has become the focus of 4D mmWave radar development.
Qingmian Wan +5 more
doaj +1 more source
CancersCancer heterogeneity is a major challenge in oncology, complicating diagnosis, prognostication, and treatment. The clinical heterogeneity of cancer, which leads to differential treatment outcomes between patients with histopathologically similar cancers, is attributable to molecular diversity manifesting through genetic, epigenetic, transcriptomic ...
William J. MacDonald +5 more
openaire +2 more sources