Results 121 to 130 of about 432,033 (303)

Research on Private Network Architecture and Key Technologies for Enterprise Multi-Agents Collaboration

open access: yesDianxin kexue
Artificial intelligence (AI) is evolving from a stage dominated by large language models (LLMs) towards autonomously collaborative AI agents. To address the core challenges of large-scale multi-agent collaboration in enterprise digital transformation ...
HAN Zhengxin   +5 more
doaj  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

ORCH: many analyses, one merge—a deterministic multi-agent orchestrator for discrete-choice reasoning with EMA-guided routing

open access: yesFrontiers in Artificial Intelligence
IntroductionMulti-agent/ensemble approaches can improve discrete-choice reasoning with large language models, but common orchestration methods are often non-deterministic, expensive, and difficult to reproduce.
Hanlin Zhou, Hanlin Zhou, Huah Yong Chan
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Weird Ties? Growth, Cycles and Firm Dynamics in an Agent-Based Model with Financial-Market Imperfections [PDF]

open access: yes
This paper studies how the interplay between technological shocks and financial variables shapes the properties of macroeconomic dynamics. Most of the existing literature has based the analysis of aggregate macroeconomic regularities on the ...
Domenico Delli Gatti   +3 more
core  

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

The Impacts of Structural Changes in the Labor Market: a Comparative Statics Analysis Using Heterogeneous-agent Framework [PDF]

open access: yes
In this paper we aim at analyzing the impacts on welfare and wealth and consumption distribution across different labor market structural features. In particular, we pursue a steady-state analysis to assess the impacts of unit vacancy costs, unemployment
Ana Paula Ribeiro, Carlos Miguel Silva
core  

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Improving Reinforcement Learning Experiments in Unity through Waypoint Utilization

open access: yesProceedings of the International Florida Artificial Intelligence Research Society Conference
Multi-agent Reinforcement Learning (MARL) models teams of agents that learn by dynamically interacting with an environment and each other, presenting opportunities to train adaptive models for team-based scenarios.
Caleb Koresh   +3 more
doaj   +1 more source

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