Results 91 to 100 of about 781,166 (294)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Phase coexistence in the fully heterogeneous Hegselmann–Krause opinion dynamics model
Scientific ReportsWe present an extensive study of the joint effects of heterogeneous social agents and their heterogeneous social links in a bounded confidence opinion dynamics model.
Rémi Perrier +2 more
doaj +1 more source
Exogenous Targeting Instruments with Heterogeneous Agents [PDF]
This paper investigates the ability of ambient pollution instruments to induce a group of heterogeneous agents to choose a target outcome. Six controlled laboratory sessions were conducted with heterogeneous agents facing ambient pollution instruments ...
John Spraggon
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Using genetic algorithms to model the evolution of heterogeneous beliefs [PDF]
Genetic algorithms have been used by economists to model the process by which a population of heterogeneous agents learn how to optimize a given objective.
James Bullard, John Duffy
core
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
A Note on Equity Premia in Markets with Heterogeneous Agents [PDF]
We analyze a static partial equilibrium model where the agents are not only heterogeneous in their beliefs about the return on risky assets but also in their attitude to it. While some agents in the economy are subjective utility maximizers others behave
Tatjana Chudjakow
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Couple-Group Consensus: A Class of Delayed Heterogeneous Multiagent Systems in Competitive Networks
Complexity, 2018 This paper discusses the couple-group consensus issues of a class of heterogeneous multiagent systems containing first-order and second-order dynamic agents under the influence of both input and communication delays. In distinction to the existing works,
Lianghao Ji, Yue Zhang, Yiliu Jiang
doaj +1 more source
Axiomatic resource allocation for heterogeneous agents [PDF]
We analyze a model of resource allocation in which agents' abilities (to transform the resource into an interpersonally comparable outcome) and initial endowments may differ.
MORENO-TERNERO, Juan D., ROEMER, John E.
core