Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong +6 more
wiley +1 more source
A nanomagnetic triazole-based Schiff-base complex of palladium(0) as an efficient heterogeneous catalyst for the Mizoroki-Heck C-C cross-coupling reaction under green conditions. [PDF]
Mehdar YTH +5 more
europepmc +1 more source
Single‐Mitochondrion ATP Profiling Directs Discovery of Targetable OXPHOS Dependency in Cancers
MitoATP‐nFCM integrates nano‐flow cytometry with fluorogenic probes (ATP/membrane potential) and antibodies to quantify mitochondrial metabolites and protein expression at single‐organelle resolution, exposing oxidative phosphorylation (OXPHOS)‐driven metabolic rewiring in cancers.
Xu Xiao +7 more
wiley +1 more source
Tetrahydrodipyrazolopyridine covalently immobilized on silica-coated magnetic nanoparticles as a basic heterogeneous catalyst for multicomponent synthesis of dihydropyrano[2,3-c]pyrazole derivatives and Knoevenagel condensation. [PDF]
Saffar A.
europepmc +1 more source
A large‐scale multiomic dataset (proteomic and metabolomic) comprising 3,060 plasma samples were analyzed to identify proteins, metabolites, pathways, and protein‐associated drugs linked to Alzheimer’s Disease (AD) independently of apolipoprotein E (APOE). AD was associated with a distinct molecular signature that captures.
Fuhai Li +22 more
wiley +1 more source
SiO<sub>2</sub>@Benzothiazole-Cl@Fc as an Efficient Heterogeneous Catalyst for the Synthesis of 1,3,5-Trisubstituted Pyrazoles by A<sup>3</sup> Coupling. [PDF]
Sead FF +8 more
europepmc +1 more source
The Uppsala APP Mutation Promotes Wild‐Type Amyloid‐β Aggregation and Deposition In Vivo
We investigated in vivo cross‐seeding of amyloid‐β (Aβ) isoforms in transgenic mice co‐expressing wild‐typeAβ and the Uppsala‐mutant Aβ variant (AβUpp), lacking six central residues. Weleveraged MALDI‐MS imaging and hyperspectral microscopy to follow spatio‐temporalAβ deposition.
Junyue Ge +14 more
wiley +1 more source
Phyto-engineered Pd-doped WO<sub>3</sub> nanocomposite <i>via Anisomeles indica</i> leaf extract: a recyclable heterogeneous catalyst for aqueous Petasis reaction, photocatalytic dye degradation, and antibacterial applications. [PDF]
Pandit N +7 more
europepmc +1 more source
A Perspective on the Applications of Triphasic Gas Storage in Electrochemical Systems
Gas storage in microporous materials positioned locally at an electrode or electrocatalyst surface enhances electrochemical processes. Abstract Microporous materials store gases under dry conditions (e.g., hydrogen or oxygen via physisorption), but in some cases microporous materials also show triphasic (e.g., in a solid|gas|liquid system) gas storage ...
Zhongkai Li +9 more
wiley +1 more source

