Results 41 to 50 of about 1,157,388 (296)

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Polymer Supported Ni(salen) Catalysts and Ni(II)-salen zeolite Y as Catalysts for Heterogeneous Electrohydrocyclization Reactions

International Journal of Electrochemical Science, 2019
Polymer supported Ni(salen) and zeolite encapsulated Ni(salen) were synthesized and investigated as electrocatalysis agents in the electrohydrocyclization reaction using a reticulated vitreous carbon electrode in dimethylformamide. Cyclic voltammetry was
Brittanie A. Clendenin, James A. Miranda
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Polymer-Supported Heterogeneous Fenton Catalysts for the Environmental Remediation of Wastewater

Molecules
Materials based on polymer hydrogels have demonstrated potential as innovative Fenton catalysts for treating water. However, developing these polymer-supported catalysts with robust stability presents a significant challenge.
Bakhta Bouzayani, Maria Ángeles Sanromán   +1 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Immobilized heterogeneous catalysts for CO2 hydrogenation to formic acid: A review

Carbon Capture Science & Technology
Formic acid is a promising hydrogen storage medium that can be produced via the catalytic hydrogenation of CO2. Compared with heterogeneous catalysts, homogeneous catalysts composed of organic metal complexes, especially Ru- and Ir-based catalysts, show ...
Hongwei Li, Bo Peng, Shuaishuai Lv, Qiuming Zhou, Zhennan Yan, Xuebin Luan, Xuandong Liu, Congcong Niu, Yanfang Liu, Jili Hou, Zhiqiang Wang, Ying Chen, Binhang Yan, Zhigang Tang, Chaopeng Hou, Kang Qin, Yu Wu, Run Xu   +17 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Potential of SO42-/ ZnO Acid Catalyst for Heterogeneous Transesterification of Vegetable Oil to Biodiesel [PDF]

, 2012
Among the possible renewable energy resources, diesel fuels derived from triglycerides of vegetable oils and animal fats have shown potential as substitutes for petroleum-based diesel fuels.
I. , Istadi, Roikhatus , Solikhah, Didi , D. Anggoro, Luqman , Buchori, Inshani , Utami   +4 more
core   +1 more source

A Review on Bio-Based Catalysts (Immobilized Enzymes) Used for Biodiesel Production

Energies, 2020
The continuous increase of the world’s population results in an increased demand for energy drastically from the industrial and domestic sectors as well.
Samuel Santos, Jaime Puna, João Gomes
doaj   +1 more source