Results 51 to 60 of about 6,378,755 (279)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

High Availability Optimization in Heterogeneous Cellular Networks [PDF]

open access: yes2016 IEEE Global Communications Conference (GLOBECOM), 2016
The exponential growth in data traffic and dramatic capacity demand in fifth generation (5G) has inspired the move from traditional single-tier cellular networks towards heterogeneous cellular networks (HetNets). To face the coming trend in 5G, the high availability requirement in new applications, needs to be satisfied to achieve low latency service ...
Jie Jia 0001   +4 more
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Network-Coded Multigeneration Protocols in Heterogeneous Cellular Networks [PDF]

open access: yes, 2018
In the upcoming era of 5G, the number of devices will increase massively, defining a heterogeneous wireless network. Nodes will be gathered in Mobile Clouds, and communicate between peers to achieve a general benefit. To provide packet resilience, error correction codes will be used. In particular, Random Linear Network Coding is standing out as one of
Roberto Torre Arranz   +2 more
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Towards 5G:heterogeneous cellular network architecture design based on intelligent SDN paradigm

open access: yesDianxin kexue, 2016
To enrich the SDN(software defined networking)with intelligence and learning capability,an intelligent SDN paradigm was proposed for the first time.Combining it with the traditional cellular networks,5G-oriented heterogeneous cellular network ...
Yifan ZHOU, Zhifeng ZHAO, Honggang ZHANG
doaj   +2 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Bounds on the coverage probability of heterogeneous cellular networks [PDF]

open access: yes2016 IEEE International Conference on Communications Workshops (ICC), 2016
In a heterogeneous cellular network (HCN), multiple tiers are employed to improve the network coverage probability. For this purpose, different properties of the coverage probability of an HCN should be studied carefully. This paper is classified into two main parts. First, a tight upper bound for the coverage probability of an HCN is derived.
Morteza Banagar   +2 more
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The Coexistence of D2D Communication under Heterogeneous Cellular Networks (HetNets) [PDF]

open access: yes, 2019
Device-to-Device (D2D) communication is a promising technique for supporting the stringent requirements of the fifth-generation cellular network (5G).
Algedir, Amal
core  

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