Results 171 to 180 of about 44,232 (283)

Smart Integration of Structural Biology and Medicinal Chemistry to Unlock Target‐Driven Drug Discovery

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT To enhance drug discovery efforts, medicinal chemists should evaluate, filter, and utilize relevant structural information about target proteins. Acquiring and interpreting protein structures is crucial for elucidating ligand‐receptor interactions and addressing ADME‐related considerations, making it an essential aspect of medicinal chemistry.
Matteo Rossi Sebastiano   +4 more
wiley   +1 more source

DeepSeek‐Lattice‐KG: A Compact Language Model With Knowledge Graph Augmentation for Lattice Structure Design

open access: yesMaterials Genome Engineering Advances, EarlyView.
DeepSeek‐Lattice‐KG integrates a domain‐adapted 14B LLM with a Neo4j lattice knowledge graph distilled from 50,000 papers. It analyzes queries, retrieves supporting subgraphs, and generates grounded answers; on a 2100‐question, six‐domain benchmark, it achieves 94.8% accuracy.
Zhiyang Shu   +6 more
wiley   +1 more source

Medicane characteristics from high‐resolution satellite radar observations

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
This study uses high‐resolution observations from satellite synthetic aperture radar (SAR) to reveal that medicanes, cyclones with tropical features in the Mediterranean basin, have dynamical characteristics with attributes comparable with those of tropical cyclones of similar intensities, but smaller outer sizes and Rossby numbers.
Arthur Avenas   +6 more
wiley   +1 more source

Survey on AI‐Enabled Computer Vision Technologies and Applications for Space Robotic Missions

open access: yesJournal of Field Robotics, EarlyView.
ABSTRACT This survey provides a comprehensive overview of recent advancements and challenges in Artificial Intelligence (AI)‐enabled computer vision (CV) techniques for space robotic missions, spanning critical phases such as Entry, Descent, and Landing (EDL), orbital operations, and planetary surface exploration.
Maciej Quoos   +6 more
wiley   +1 more source

Wall‐to‐wall Amazon forest height mapping with Planet NICFI, Aerial LiDAR, and a U‐Net regression model

open access: yesRemote Sensing in Ecology and Conservation, EarlyView.
Tree canopy height is a key indicator of forest biomass and structure, yet accurate mapping across the Amazon remains challenging. Here, we generated a canopy height map of the Amazon forest at ~4.8 m resolution using Planet NICFI imagery and a deep learning U‐Net model trained with airborne LiDAR data.
Fabien H. Wagner   +21 more
wiley   +1 more source

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