Results 31 to 40 of about 5,836 (255)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Heterogeneous Phases Reaction Equilibrium in an Oxy-Thermal Carbide Furnace

open access: yesChemEngineering, 2020
This work focuses on revealing the chemical reaction equilibrium behaviors of gas−liquid−solid heterogeneous phases in an oxy-thermal carbide furnace.
Wenjie Xiong   +6 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Vaccination Games with Peer Effects in a Heterogeneous Hospital Worker Population

open access: yesAdministrative Sciences, 2015
We develop a game theoretic model to analyze the Nash equilibrium of vaccine decisions in a hospital population with heterogeneous contacts. We use the model in conjunction with person-to-person contact data within a large university hospital.
Troy Tassier   +2 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Thermodynamic Stability Areas of Polyvanadates of Alkaline Earth Metals

open access: yesJournal of Chemistry, 2019
A thermodynamic method of the global Gibbs energy variation calculation for describing heterogeneous equilibria of transformations of calcium, strontium, and barium polyvanadates, that occur in systems MeO-V2O5-H2O, where Me is the alkaline earth element,
Igor Povar   +3 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Multistability for a Mathematical Model of the Dynamics of Predators and Preys in a Heterogeneous Area

open access: yesСовременная математика: Фундаментальные направления, 2022
We consider the system of reaction-diffusion-advection equations describing the evolution of the spatial distributions of two populations of predators and two prey populations.
T. D. Ha, V. G. Tsybulin
doaj   +1 more source

Swelling equilibria for heterogeneous polyacrylamide gels [PDF]

open access: yesJournal of Applied Polymer Science, 1996
To correlate swelling equilibria for heterogeneous polyacrylamide gels in water to the monomer concentration at preparation, it is necessary to modify the classic Flory–Rehner theory. The necessary modification concerns the relation which links the number of segments between juction points to the monomer concentration at preparation; that relation is ...
Toshiaki Hino, John M. Prausnitz
openaire   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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