Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans +7 more
wiley +1 more source
Impact of Ferrite-Cementite Microstructure on Tensile and Cutting Behaviour of C75S Steel. [PDF]
Kaczmarczyk J.
europepmc +1 more source
Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong +12 more
wiley +1 more source
Microstructure and Mechanical-Tribological Properties of HVOF-Sprayed (WC-Co+Ni) Coatings on Ductile Cast Iron. [PDF]
Ksiazek M, Boron L, Tchorz A.
europepmc +1 more source
The Y supersaturation in the [Ba‐Cu(I/II)‐O] transient liquid composition is the driving force toward YBCO nucleation and growth in TLAG. Tuning the initial (Ba:Cu) molar ratio in the ink composition determines the YBCO epitaxial nucleation through supersaturation control.
Lavinia Saltarelli +12 more
wiley +1 more source
Heterogeneity-Driven Strengthening and Hardening in Heterostructured Materials: Modeling and Simulation Across Length Scales. [PDF]
Zhou C, Rohoman MM, Li N.
europepmc +1 more source
Eutectozymes as Soft Hybrid Materials for Advanced Biocatalysis
Eutectozymes are sustainable hybrid materials that embed a GOx–HRP cascade within hydrophobic eutectogels featuring a dual supramolecular–covalent network. This architecture preserves native enzyme structure and stability, enables efficient heterogeneous biocatalysis in aqueous media, and positions eutectogels as robust platforms for next‐generation ...
Manuel Eduardo Martinez Cartagena +10 more
wiley +1 more source
The Influence of SiC and Al<sub>2</sub>O<sub>3</sub> Particles on the Microstructure and Tribological Properties of the EN-GJL-150 Cast Iron-Based Composite. [PDF]
Piatkowski J +3 more
europepmc +1 more source
Residual magnetization induces pronounced mechanical anisotropy in ultra‐soft magnetorheological elastomers, shaping deformation and actuation even without external magnetic fields. This study introduces a computational‐experimental framework integrating magneto‐mechanical coupling into topology optimization for designing soft magnetic actuators with ...
Carlos Perez‐Garcia +3 more
wiley +1 more source
A Heterogeneously structured Mg-Zn laminate alloy for gradient degradation behavior. [PDF]
Zhang X +9 more
europepmc +1 more source

