Results 141 to 150 of about 356,350 (266)

Heterogeneous network propagation with forward similarity integration to enhance drug-target association prediction. [PDF]

PeerJ Comput Sci, 2022
Tangmanussukum P, Kawichai T, Suratanee A, Plaimas K.   +3 more
europepmc   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

scXDR: drug response prediction across single-cell datasets via heterogeneous network transfer learning. [PDF]

Commun Biol
Qi G, Wang L, Nan M, Fu Y, Ren Q, Zhang Y, Sun Z, Shi Z, Lu J, Gao J.   +9 more
europepmc   +1 more source

Predictive analysis of multiple future scientific impacts by embedding a heterogeneous network. [PDF]

PLoS One, 2022
Ochi M, Shiro M, Mori J, Sakata I.
europepmc   +1 more source

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi, Daniel P. O. Kaiser, Martin Arndt, Norma J. Diel, Erik Simon, Witold H. Polanski, Volker Puetz, Hagen B. Huttner, Timo Siepmann   +8 more
wiley   +1 more source

MetaMDA: explainable prediction of microbe-drug association utilizing random walks on a microbe-metabolite-drug heterogeneous network. [PDF]

Bioinformatics
Wang Q, Chen S, Miao X, Liu Y, Liu B.
europepmc   +1 more source

Fractional model for Middle East respiratory syndrome coronavirus on a complex heterogeneous network. [PDF]

Sci Rep, 2022
El-Saka HAA, Obaya I, Lee S, Jang B.
europepmc   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

THGC_MDA: a method for predicting the associations between m¹A modification and diseases based on ternary heterogeneous network and graph convolutional neural network. [PDF]

Front Genet
Gao H, Zhou X, Bai L, Yang H, Liu F.
europepmc   +1 more source

A novel bi-directional heterogeneous network selection method for disease and microbial association prediction. [PDF]

BMC Bioinformatics, 2022
Guan J, Zhang ZG, Liu Y, Wang M.
europepmc   +1 more source