ERFMTDA: Predicting tsRNA-disease associations using an enhanced rotative factorization machine. [PDF]
Lan W +6 more
europepmc +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
ARMOR: Pareto-Aware Dynamic Routing for Energy-Efficient Heterogeneous Multimodal Perception in Autonomous Driving. [PDF]
Liu J, Zhang Y, Chen Y, Wang Y.
europepmc +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
On a Computational Strategy with Time-Space Homogenization for Heterogeneous Materials
Nouy, Anthony, Ladevèze, Pierre
doaj +1 more source
How Early Is Early? Defining Functional Rehabilitation After Acute Achilles Tendon Rupture: A Narrative Review. [PDF]
Hashimoto M +4 more
europepmc +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Imaging-Guided Versus Conventional Ventricular Tachycardia Ablation in Ischemic Cardiomyopathy: A Systematic Review and Meta-Analysis. [PDF]
Ahmed S, Sawalha K, Sharief M, Ammar A.
europepmc +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
The Role of Intermittent Fasting in Rheumatoid Arthritis-A Scoping Review. [PDF]
Winiarska M +2 more
europepmc +1 more source

