Results 181 to 190 of about 15,814,880 (256)

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

System-level integration of halide perovskite optoelectronics for its commercial deployment. [PDF]

Nat Commun
Yang W, Yang X, Su R, Feng Y, Zhao L, Li M, Wang X, Zhu R, Pan C, Luo D.   +9 more
europepmc   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Rubisco kinetic acclimation at the holoenzyme level. [PDF]

Proc Natl Acad Sci U S A
Askey B, Ceminsky M, Scott E, Wang Y, Oh ZG, Azinas S, Laganowsky A, Gunn LH.   +7 more
europepmc   +1 more source

On the micro-heterogeneous structure of neat and aqueous propylamine mixtures: A computer simulation study

, 2017
Martina Požar, A. Perera
semanticscholar   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

Iron Oxide-Chitosan Macroporous Nanocomposite Hydrogels for Efficient Heterogeneous Electro-Fenton Degradation of Ciprofloxacin. [PDF]

Gels
Pelayo-Vázquez JB, Osuna-Laveaga DR, Peña-Jaramillo JP, Gómez-Salazar S, Moreno-Medrano ED, Pérez-García MG.   +5 more
europepmc   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Graph-based RNA structural representation reveals determinants of subcellular localization. [PDF]

Brief Bioinform
Hao Y, Sun H, Ran Z, Guo X, Liu M, Bi Y, Polo J, Liu N, Li F.   +8 more
europepmc   +1 more source

Organized chaos in Kupffer's vesicle: how a heterogeneous structure achieves consistent left-right patterning. [PDF]

Bioarchitecture, 2014
Smith DJ, Montenegro-Johnson TD, Lopes SS.   +2 more
europepmc   +1 more source