Results 41 to 50 of about 164,630 (354)

Heterosexual HIV-1 transmission after initiation of antiretroviral therapy: a prospective cohort analysis

The Lancet, 2010
Background High plasma HIV-1 RNA concentrations are associated with increased risk of HIV-1 transmission. Initiation of antiretroviral therapy (ART) reduces plasma HIV-1 concentrations, but little empiric data are available on the rate of sexual HIV-1 ...
D. Donnell, J. Baeten, J. Kiarie, Katherine K. Thomas, W. Stevens, C. Cohen, J. McIntyre, J. Lingappa, C. Celum   +8 more
semanticscholar   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Sexual behaviour in Britain: early heterosexual experience.

, 2001
BACKGROUND: Relatively high rates of teenage conception and sexually transmitted infection among young people in Britain have focused attention on early sexual behaviour and its determinants.
Nanchahal, K, McManus, S, Erens, B, Korovessis, C, Macdowall, W, Mercer, CH, Field, J, Copas, AJ, Wellings, K, Fenton, KA, Johnson, AM   +10 more
core   +1 more source

Characteristics of LGBTQ+ Patients and Their Care in Comparison with Heterosexual Individuals: What Is Important for the OBGYN?

Medicina
Background and Objectives: Women of the LGBTQ+ community, like heterosexual women, face a wide range of health issues and have a right to comprehensive healthcare.
Gabija Didžiokaitė, Paulina Leškevičiūtė, Aida Kuznecovaitė, Virginija Paliulytė   +3 more
doaj   +1 more source

“Since both of us are using antiretrovirals, we have been supportive to each other”: facilitators and barriers of pre‐exposure prophylaxis use in heterosexual HIV serodiscordant couples in Kisumu, Kenya

Journal of the International AIDS Society, 2016
Introduction Since 2015, the World Health Organization recommends pre‐exposure prophylaxis (PrEP) for all persons at substantial risk for HIV, including HIV‐uninfected partners in serodiscordant relationships in resource‐limited settings.
Rena C Patel, Gaelen Stanford‐Moore, Josephine Odoyo, Maria Pyra, Imeldah Wakhungu, Keerthana Anand, Elizabeth A Bukusi, Jared M Baeten, Joelle M Brown   +8 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Canadian undergraduate men’s visual attention to cisgender women, cisgender men, and feminine trans individuals

Scientific Reports, 2021
Some heterosexual men express sexual interest in feminine trans individuals with penises. It is possible that this interest arises from a tendency for heterosexual men to be sexually responsive to gender in addition to sex.
Lanna J. Petterson, Paul L. Vasey
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

A qualitative exploration of whether lesbian and bisexual women are 'protected' from sociocultural pressure to be thin [PDF]

, 2014
Heterosexual women in Western cultures are known to experience body image concerns, dieting and disordered eating as a result of intense social pressures to be thin. However, it is theorised that lesbian and bisexual women belong to a subculture that is ‘
Huxley, Caroline, Clarke, Victoria, Huxley, Caroline J., Halliwell, Emma   +3 more
core   +1 more source

Heterosexual and non-heterosexual identities and queer-blindfolding

, 2022
The understanding of group-based discrimination and its structural underpinnings has gained depth, exploring how marginalised groups are affected and the role of dominant group members in its reproduction and contestation.
Enzo Cáceres
core   +1 more source