Results 201 to 210 of about 8,590 (232)
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The theory of inbreeding with forced heterozygosis
Journal of Genetics, 1935When a foreign gene is being bred into a pure line, or when a population with a lethal gene, incomplete sex linkage, heterostylism, or self-sterility is being inbred, the population is kept heterozygous for a particular gene or chromosome segment, but otherwise inbred.
M. S. Bartlett, J. B. S. Haldane
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Heterozygosis and genetic recombination in herpes simplex type 1 virus
Virology, 1977Abstract Two- and three-factor crosses with temperature-sensitive (ts) and syncytial plaque morphology (syn) mutants of herpes simplex type 1 virus have been used to study the possible role of syn-syn+ mixed plaque-forming virus in genetic recombination.
D A, Ritchie +3 more
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A Compound Heterozygosis of Two Novel Mutations in vWF Exacerbates vWD in a Chinese Pedigree.
Clinical LaboratoryBACKGROUND von Willebrand disease (vWD), caused by mutations in the von Willebrand factor (vWF) coding gene, is a disease characterized by abnormal coagulation activity and a severe tendency for hemorrhage.
Jiajia Hu +6 more
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Structural heterozygosis in man: analysis of two families
Annals of Human Genetics, 1962SummaryTwo families are described in each of which the father is presumed to have an autosomal reciprocal translocation as a result of which both children in one family, and one of three children in the other, are grossly abnormal. The reciprocal translocations are probably between chromosomes nos. 9 and 4 in the first family, and chromosomes nos.
J. H. EDWARDS +5 more
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Electrophoretic demonstration of heterozygosis in hereditary pyruvate kinase deficiency
Human Genetics, 1979The defective PK variant of a patient with a severe form of hemolytic anemia was characterized by its inability to undergo a normal 'proteolytic maturation.' In obligatory heterozygotes it could be proved that red cells contained different PK species, some of them sensitive and the others partially resistant to the action of trypsin.
A, Kahn, J, Marie, J L, Vives-Corrons
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Neurology, 2015
OBJECTIVE: To determine the genetic cause of glycogen branching enzyme (GBE) deficiency leading to late onset glycogenosis type IV BACKGROUND: Adult polyglucosan body disease (APBD) is a rare autosomal recessive disorder, caused by pathogenic mutations ...
Orhan H. Akman +4 more
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OBJECTIVE: To determine the genetic cause of glycogen branching enzyme (GBE) deficiency leading to late onset glycogenosis type IV BACKGROUND: Adult polyglucosan body disease (APBD) is a rare autosomal recessive disorder, caused by pathogenic mutations ...
Orhan H. Akman +4 more
semanticscholar +1 more source
Severe prekallikrein deficiency due to a compound heterozygosis in the KLKB1-gene
Hämostaseologie, 2009SummaryA 14 year old boy was referred to us for a detailed coagulation study because a previously performed aPTT has been found prolonged. The boy had no history of bleeding symptoms and also the family history was negative for bleeding or thrombotic events. The aPTT in the patient was 96 s (reference range: 24–36 s), prothrombin time and thrombin time
Bernhard, Maak +3 more
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Structural heterozygosis at genes IL V2 and IL V5 in Saccharomyces carlsbergensiss
Current Genetics, 1987Chromosomes XII and XIII of a Saccharomyces carlsbergensis brewing strain were analysed after their transfer into Saccharomyces cerevisiae by kar1-mediated single chromosome transfer. The lager yeast was found to be heterozygous for the isoleucine-valine biosynthesis genes IL V2 (encoding acetohydroxy acid synthase) and IL V5 (encoding acetohydroxy ...
J. G. L. Petersen +4 more
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