Results 91 to 100 of about 3,081,667 (237)

More evidence for widespread antagonistic pleiotropy in polymorphic disease alleles

open access: yesFrontiers in Genetics
IntroductionMany loci segregate alleles classified as “genetic diseases” due to their deleterious effects on health. However, some disease alleles have been reported to show beneficial effects under certain conditions or in certain populations.
Cynthia Lockwood   +3 more
doaj   +1 more source

Recombining your way out of trouble: the genetic architecture of hybrid fitness under environmental stress [PDF]

open access: yes, 2020
Hybridization between species is a fundamental evolutionary force that can both promote and delay adaptation. There is a deficit in our understanding of the genetic basis of hybrid fitness, especially in non-domesticated organisms.
Bendixsen, D.   +5 more
core   +1 more source

The shibirets4 mutation causes temperature sensitive paralytic and lethal phenotypes in the Queensland fruit fly, Bactrocera tryoni

open access: yesInsect Science, EarlyView.
Abstract Bactrocera tryoni, the Queensland fruit fly, is among the most damaging insect pests to the Australian horticultural industry as larvae infest ripening fruits or vegetables prior to harvest. Genetic biocontrol using Sterile Insect Technique (SIT) programs have been used to successfully suppress populations, via mass release of factory‐reared ...
Anzu Okada   +7 more
wiley   +1 more source

Behavioral cost & overdominance in Anopheles gambiae. [PDF]

open access: yesPLoS ONE, 2015
In response to the widespread use of control strategies such as Insecticide Treated Nets (ITN), Anopheles mosquitoes have evolved various resistance mechanisms.
Malal M Diop   +9 more
doaj   +1 more source

Replicators in Fine-grained Environment: Adaptation and Polymorphism

open access: yes, 2009
Selection in a time-periodic environment is modeled via the two-player replicator dynamics. For sufficiently fast environmental changes, this is reduced to a multi-player replicator dynamics in a constant environment.
Armen E. Allahverdyan   +10 more
core   +1 more source

Neoclassical development of genetic sexing strains for insect pest and disease vector control

open access: yesInsect Science, EarlyView.
The sterile insect technique has been effectively used for decades, and an important component is the availability of sex separation systems, in particular genetic sexing strains. Classical approaches, such as irradiation‐induced chromosomal translocations, have yielded stable strains for species like the Mediterranean fruit fly.
Giovanni Petrucci   +5 more
wiley   +1 more source

Improving sequence-based genotype calls with linkage disequilibrium and pedigree information

open access: yes, 2012
Whole and targeted sequencing of human genomes is a promising, increasingly feasible tool for discovering genetic contributions to risk of complex diseases.
Whittemore, Alice S., Zhou, Baiyu
core   +1 more source

Microhaplotype Methods Enable Relationship Inference in a Bottlenecked Mammalian Species

open access: yesAnimal Conservation, EarlyView.
Northern elephant seals (Mirounga angustirostris) are among the most genetically depauperate mammals in the world. A near‐total population bottleneck in the 19th century, coupled with the breeding system of extreme polygyny, has challenged efforts to estimate individual reproductive success with genetic methods.
Keith M. Hernandez   +6 more
wiley   +1 more source

Isolation mediates persistent founder effects on zooplankton colonisation in new temporary ponds [PDF]

open access: yes, 2017
Understanding the colonisation process in zooplankton is crucial for successful restoration of aquatic ecosystems. Here, we analyzed the clonal and genetic structure of the cyclical parthenogenetic rotifer Brachionus plicatilis by following populations ...
Badosa, Anna   +4 more
core   +2 more sources

Luteinizing hormone receptor knockout mouse: What has it taught us?

open access: yesAndrology, EarlyView.
Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley   +1 more source

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