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Biodegradation of hexachlorocyclohexane (HCH) by microorganisms
Biodegradation, 2005The organochlorine pesticide Lindane is the gamma-isomer of hexachlorocyclohexane (HCH). Technical grade Lindane contains a mixture of HCH isomers which include not only gamma-HCH, but also large amounts of predominantly alpha-, beta- and delta-HCH. The physical properties and persistence of each isomer differ because of the different chlorine atom ...
Theresa M, Phillips +3 more
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Hexachlorocyclohexane: persistence, toxicity and decontamination
Reviews on Environmental Health, 2014Abstract Hexachlorocyclohexane (HCH), a persistent organochlorine insecticide, has been extensively used in the past for control of agricultural pests and vector borne diseases. The use of HCH has indeed accrued benefits, however the unusual production of the insecticidal isomer; γ-HCH (lindane) and unregulated disposal of HCH muck has ...
Namita, Nayyar +9 more
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Microbial Transformation of Hexachlorocyclohexane
Zentralblatt für Mikrobiologie, 1991Some microorganisms are able to accumulate and to metabolize the pesticide lindane (gamma-hexachlorocyclohexane, gamma-HCH) and other HCH-isomers. Microbial activities, detected metabolites, transformation rates, concentrating factors are reviewed. The results are discussed in respect to use microbiological processes for purification of contaminated ...
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Hexachlorocyclohexanes in the North American Atmosphere
Environmental Science & Technology, 2004Annually integrated air concentrations of alpha- and gamma-hexachlorocyclohexane (HCH) were determined in 2000/2001 at 40 stations across North America using XAD-based passive air samplers to understand atmospheric distribution processes on a continental scale.
Li, Shen +5 more
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Hexachlorocyclohexanes in human blood serum
Journal of Chromatography A, 1997A simplified method allowing the determination of trace concentrations (ng/ml) of hexachlorocyclohexanes in human sera suitable for the analysis of large numbers of samples has been developed. Comparison of acid (conc. H2SO4,) and basic (5 M KOH) digestion has shown that good recoveries are obtained with the former when an internal standard, 1,2,4,5 ...
R, Otero +2 more
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Biochemical Effects Induced by the Hexachlorocyclohexanes
2011The hexachlorocyclohexanes (HCHs) are synthetic compounds that have been widely used for the control of pests. The most common HCH isomers are the α-, β-, δ-, and γ-HCH. Although the have the same chlorine substitution pattern, the spatial orientation of chlorine atoms is different on each one of them, resulting in unique structures that have distinct ...
Jesus, Olivero-Verbel +2 more
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HEXACHLOROCYCLOHEXANE IN SCABIES
Journal of the American Medical Association, 1949To the Editor:— I am sorry if in my letter inThe Journal, Dec. 25, 1948, page 1253, undue stress was placed on the possible toxicity of hexachlorocyclohexane when used in the treatment of scabies. My chief concern was and is over the widespread use of this material in the South as an insecticide dust for cotton.
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Biodegradation of alpha-hexachlorocyclohexane
Naunyn-Schmiedeberg's Archives of Pharmacology, 1975Alpha-hexachlorocyclohexane (alpha-HCH) is dechlorinated by enzymes contained in rat liver cytosol and microsomes. An evidence was obtained that in the cytosol there are two alpha-HCH dechlorinating enzymes at least; one operates only in the presence of reduced glutathione (GSH) and catalyzes dechlorinations associated with the formation of another ...
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Biodegradation of Hexachlorocyclohexane in Soil
1995The insecticide lindane (γ-HCH) is the most known HCH isomer. During HCH production only 17% of the reaction product is γ-HCH. The remaining part consists of α-, s-, δ- and e-HCH, that have an insignificant insecticide activity. These inactive isomers were discarded by the chemical industry (Bachmann et al., 1988a) which has caused large amounts of ...
H. H. M. Rijnaarts +2 more
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Stereospecificity in the cytotoxic action of hexachlorocyclohexane isomers
Chemico-Biological Interactions, 2010Hexachlorocyclohexane (HCH) is a highly recalcitrant organochlorine insecticide known for its chronic toxicity. In spite of many isolated studies a clear mechanism of cytotoxic action of HCH and the structure-toxicity relationship of its isomers is not well understood.
Anup, Srivastava, T, Shivanandappa
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