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Hexavalent chromium disrupts chromatin architecture

Seminars in Cancer Biology, 2021
Accessibility of DNA elements and the orchestration of spatiotemporal chromatin-chromatin interactions are critical mechanisms in the regulation of gene transcription. Thus, in an ever-changing milieu, cells mount an adaptive response to environmental stimuli by modulating gene expression that is orchestrated by coordinated changes in chromatin ...
Andrew VonHandorf   +2 more
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Avoiding Hexavalent Chromium

Fastening and Assembly Solutions and Technology, 2022
The Academy Award-nominated film ‘Erin Brockovich’ (2000) tells the true story of a woman who fought a utility company that was polluting the water supply of the surrounding community with a cancer-causing chemical waste compound. Over two decades later, that same substance is still used as a rust-inhibiting plating on industrial fasteners, according ...
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Hexavalent chromium: Regulation and health effects

Journal of Trace Elements in Medicine and Biology, 2021
Despite the knowledge about heavy metals toxicity on humans, its use is widely spread mainly for industrial processes. Chromium is an element that belongs to this group and although it is present in our daily diet, it can also be harmful for humans, causing skin allergies and increasing the risk of lung cancer, among other health effects reported.
Carla Cedillo Alvarez   +2 more
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Hexavalent chromium reduction by gallic acid

Chemosphere, 2021
Cr(VI) is widely used in industry and often large quantities have been accidently or due to lack of precautions released at the environment. The presence of high concentrations of Cr(VI) in waste streams causes concern due to its toxicity and solubility. However the Cr(III) is a useful micronutrient in human diet.
Christiana, Mystrioti   +3 more
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Dermatological Toxicity of Hexavalent Chromium

Critical Reviews in Toxicology, 2007
Hexavalent chromium causes two types of dermatological toxicities: allergic contact dermatitis (ACD) and skin ulcers. This report reviews the etiology, prevalence, pathology, dose-response, and prognosis of both of these reactions. Reports in the literature indicate that repeated exposure to hexavalent chromium in concentrations of 4-25 ppm can both ...
Susan R, Shelnutt   +2 more
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Evidence of Hexavalent Chromium Ingestion

Journal of Forensic Sciences, 2003
Abstract We describe the application of histochemical demonstration of chromium in a case of fatal ingestion of potassium dichromate in a suicide attempt. Using 2-(8-quinolylazo)-4,5-di-p-tolylimidazole (QTI), we could demonstrate chromium in the erythrocyte of the victim, in situ.
Hiroshi, Kinoshita   +7 more
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Isolation of hexavalent chromium-reducing anaerobes from hexavalent-chromium-contaminated and noncontaminated environments

Applied Microbiology and Biotechnology, 1996
Hexavalent chromium [Cr(VI)], is a toxic, water-soluble contaminant present in many soils and industrial effluents. Bacteria from various soils were examined for Cr(VI) resistance and reducing potential. Microbes selected from both Cr(VI)-contaminated and -noncontaminated soils and sediments were capable of catalyzing the reduction of Cr(VI) to Cr(III)
C E, Turick, W A, Apel, N S, Carmiol
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Hexavalent Chromium Substitution

2014
From razor thin tool blade coatings to shiny custom motorcycle parts, hexavalent chromium (Hex-chrome) has historically been the coating of choice for a vast array of industrial applications. Hex-chrome has many advantages over other coating alternatives including hardness, corrosion resistance, coefficient of friction, process maturity, and economic ...
Tucker, David   +3 more
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Hexavalent chromium in refractories

Refractories, 1993
The ecologically dangerous chromium oxide CrO3 is formed in refractories on the phase boundaries. Upon contact of chromite with alkalis and the oxides CaO, BaO, and SrO, the conversion Cr3+ → Cr6+ in air is accelerated, and occurs with remarkable speed.
L. B. Khoroshavin   +3 more
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Metabolic deactivation of hexavalent chromium mutagenicity

Mutation Research/Environmental Mutagenesis and Related Subjects, 1978
Abstract Hexavalent chromium compounds (sodium dichromate, potassium chromate, chromic acid, basic zinc chromate and basic lead chromate) were found to be mutagenic for his − strains of S. typhimurium by inducing both frameshifts and base-pair substitutions.
F L, Petrilli, S, De Flora
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