Results 131 to 140 of about 7,546 (209)

Hand, Foot, and Mouth Disease in China: critical community size and spatial vaccination strategies

Hand Foot and Mouth Disease (HFMD) constitutes a considerable burden for health care systems across China. Yet this burden displays important geographic heterogeneity that directly affects the local persistence and the dynamics of the disease, and thus ...
Chang, Zhaorui, Grenfell, Bryan T., Hsiao, Victor, Lai, Shengjie, Liao, Qiaohong, Liu, Fengfeng, Metcalf, C. Jessica E., Takahashi, Saki, Van Boeckel, Thomas P., Xing, Weijia, Yu, Hongjie, Yuan, Chen, Zheng, Yaming   +12 more
core   +1 more source

Improving the inhibitors targeting enterovirus 71 3C proteinase [PDF]

, 2015
手足口病（HFMD）的频繁爆发，给许多婴幼儿带来痛苦甚至导致死亡。目前，没有任何疫苗和抗病毒治疗可用于预防和治疗手足口病。肠道病毒71型（EV71）是引起手足口病的主要病原体，它能够侵入中枢神经系统引起严重的后遗症。3C蛋白酶是EV71病毒复制过程中的一个重要蛋白酶，在EV71的成熟过程和拮抗宿主细胞的先天性免疫反应中有着重要作用。因此，EV713C蛋白酶是一个很好的抗EV71药物靶点。 AG7088最先是针对人病毒3C蛋白酶进行设计的，已被证实可有效抑制EV71病毒活性 ...
吴彩明
core  

Surveillance dan Penyebaran Penyakit Tangan, Kaki, dan Mulut (HFMD)

Cermin Dunia Kedokteran
Penyakit tangan, kaki, dan mulut atau hand, foot, and mouth disease (HFMD) merupakan penyakit virus umum yang terutama menyerang anak-anak. HFMD disebabkan oleh berbagai jenis coxsackievirus dan enterovirus, dengan penyebab utama coxsackievirus A16 dan enterovirus A71.
openaire   +1 more source

Immunopathogenesis and Virus-Host Interactions of Enterovirus 71 in Patients with Hand, Foot and Mouth Disease [PDF]

, 2017
AbuBakar, Andreoni, Ang, Arita, Arita, Bendig, Bessaud, Bracho, Brown, Castro, Chan, Chang, Chang, Chang, Chang, Chang, Chea, Chen, Chen, Chen, Chen, Chen, Chen, Cheng, Chern, Chua, Chumakov, Chung, Chung, Crabol, Drake, Feng, Fenton, Ferson, Fitzgerald, Flett, Flewett, Foo, Fujii, Fujimoto, Fukata, Gantt, Griffiths, Hagiwara, Hanson, He, Hirata, Ho, Hogarth, Hu, Huang, Huang, Huang, Huang, Hughes, Hung, Ishimaru, Kao, Kar, Kataoka, Khong, Kiener, Kim, Komatsu, Kontsek, Ku, Lee, Lee, Lei, Lei, Lei, Li, Li, Li, Liao, Lin, Lin, Lin, Lin, Lin, Lin, Lindenbaum, Liou, Liu, Liu, Liu, Liu, Lo, Lu, Lum, Machain-Williams, McMinn, McMinn, McMinn, Meng, Mirand, Mizuta, Mogensen, Morrison, Nagata, Nagata, Nagy, Nishimura, Nishimura, Ong, Ong, Ooi, Ooi, Pallansch, Pathinayake, Peng, Pilipenko, Plevka, Plevka, Plevka, Pliaka, Pérez-Ruiz, Rabenau, Reid, Rong, Rotbart, Sazaly, Schmidt, Second, Shah, Shia, Shih, Shih, Shih, Shultz, Solomon, Sutton-Hayes, Takeuchi, Tan, Tan, Tang, Tee, Thompson, Tu, Tung, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wu, Wu, Yamayoshi, Yamayoshi, Yamayoshi, Yan, Yang, Yang, Ye, Ye, Yi, Yu, Zhang, Zhang, Zhang, Zhang, Zhu, Zhu, Zhu, Zhuang   +166 more
core   +1 more source

Coxsackie Virus: The Hand, Foot, Mouth Disease (HFMD) [PDF]

Juniper Online Journal of Public Health, 2017
openaire   +1 more source

Dynamic changes of hand, foot, and mouth disease epidemic crossing three periods in Jiangxi Province, China: a long-term epidemiology retrospective study from 2009 to 2022. [PDF]

BMC Infect Dis
Hu J, Yu L, Peng Z, Pan H, Jin Y, Zeng Z, Xia G, Wang Y, Li Z, Li J, Shi Y, Xiao D, Pan H, Liu X, Zhang T.   +14 more
europepmc   +1 more source

Standardized neutralizing antibody assay for Coxsackievirus A10 in clinical trial: A framework for multivalent hand, foot, and mouth disease vaccine evaluation. [PDF]

Hum Vaccin Immunother
Wang Q, Li L, Gao J, Liu M, Wang Y, He Q, Wang W, Li Y, Gu M, Xie Z, Liu Q, Han J, Zhang Z, Guo J, Wu X, Mao Q, Chen X, Liang Z, Gao F, Ma X.   +19 more
europepmc   +1 more source

Analysis on the characteristics of delayed EV71 vaccination among children in the birth cohort from 2017 to 2022. [PDF]

Hum Vaccin Immunother
Gao J, Liu N, Zhu K, Luan L, Xu J, Zhu Y, Fan X, Wang H.   +7 more
europepmc   +1 more source

Hand-foot-and-mouth disease (HFMD) у Дніпропетровському регіоні

, 2017
Ентеровірусний везикулярний стоматит з екзантемою (Hand-Foot-and-Mouth Disease (HFMD)) - захворювання, що перебігає з ураженням шкіри кистей і стоп, слизової оболонки порожнини рота. Ентеровіруси мають тропність до нервової та серцево-судинної системи. Clinical and epidemiological particularities of HFMD in children are presented.
openaire   +1 more source

Shifting epidemiological patterns and strain replacement of hand, foot, and mouth disease in southern China, 2009-2022: A longitudinal study. [PDF]

PLoS One
Hou Y, Chen H, Jiang Y, Huang H, Tan Z, Nehl EJ, Li H, Wang J, He J, Zhong C, Wang Y, Xiao J, Chen M, Zheng Z.   +13 more
europepmc   +1 more source