Results 31 to 40 of about 4,110 (164)

Time series analysis of hand-foot-mouth disease hospitalization in Zhengzhou: establishment of forecasting models using climate variables as predictors. [PDF]

PLoS ONE, 2014
BACKGROUND: Large-scale outbreaks of hand-foot-mouth disease (HFMD) have occurred frequently and caused neurological sequelae in mainland China since 2008.
Huifen Feng, Guangcai Duan, Rongguang Zhang, Weidong Zhang   +3 more
doaj   +1 more source

Modeling Periodic HFMD with the Effect of Vaccination in Mainland China

Complexity, 2020
Hand, foot, and mouth disease (HFMD), associated with more than 20 disease-causing enteroviruses, is one of the major public health problems in mainland China, and the unique vaccine available is for enterovirus 71 (EV71). In this paper, we propose a new epidemic model to investigate the effect of EV71 vaccination on the spread of HFMD with multiple ...
Lei Shi, Hongyong Zhao, Daiyong Wu
openaire   +2 more sources

Temperature Effect on HFMD Transmission in Selangor, Malaysia

Sains Malaysiana, 2020
Hand, foot, and mouth disease (HFMD) has become a major concern for health authorities all over the world including Malaysia. In Malaysia, it has been reported that more than fifteen thousand people were affected by this disease in the year 2016 and it is suspected that climate variables play an important role in the incidence of HFMD.
Abdul Wahid, Nurmarni Athirah, Suhaila, Jamaludin, Sulekan, Ayuna   +2 more
openaire   +2 more sources

Epidemic Hand, Foot and Mouth Disease Caused by Human Enterovirus 71, Singapore

Emerging Infectious Diseases, 2003
Singapore experienced a large epidemic of hand, foot and mouth disease (HFMD) in 2000. After reviewing HFMD notifications from doctors and child-care centers, we found that the incidence of HFMD rose in September and declined at the end of October ...
Kwai Peng Chan, Kee Tai Goh, Chia Yin Chong, Eng Swee Teo, Gilbert Lau, Ai Ee Ling   +5 more
doaj   +1 more source

Discovery of Potent EV71 Capsid Inhibitors for Treatment of HFMD [PDF]

ACS Medicinal Chemistry Letters, 2017
Enterovirus 71 (EV71) is a major causative agent of hand, foot, and mouth disease (HFMD), which can spread its infections to the central nervous and other systems with severe consequences. The viral caspid protein VP1 is a well-known target for antiviral efficacy because its occupancy by suitable compounds could stabilize the virus capsid, thus ...
Peng Li, Jun Yu, Fei Hao, Haiying He, Xuyang Shi, Jiao Hu, Li Wang, Chunyan Du, Xiao Zhang, Ya Sun, Fusen Lin, Zhengxian Gu, Deming Xu, Xinsheng Chen, Liang Shen, Guoping Hu, Jian Li, Shuhui Chen, Wei Xiao, Zhenzhong Wang, Qingming Guo, Xiujuan Chang, Xuyang Tian, Tianwei Lin   +23 more
openaire   +2 more sources

Integration of a Kalman filter in the geographically weighted regression for modeling the transmission of hand, foot and mouth disease

BMC Public Health, 2020
Background Hand, foot and mouth disease (HFMD) is a common infectious disease whose mechanism of transmission continues to remain a puzzle for researchers.
Bisong Hu, Wenqing Qiu, Chengdong Xu, Jinfeng Wang   +3 more
doaj   +1 more source

Interactive effects of meteorological factors and air pollutants on hand, foot, and mouth disease in Chengdu, China: a time-series study

BMJ Open, 2022
Objectives Hand, foot, and mouth disease (HFMD) is a viral infectious disease that poses a substantial threat in the Asia-Pacific region. It is widely reported that meteorological factors are associated with HFMD.
Tao Zhang, Yue Ma, Fei Yin, Qiang Lv, Yaqiong Liu, Jiaqi Huang, Tiejun Shui   +6 more
doaj   +1 more source

Spatiotemporal cluster patterns of hand, foot, and mouth disease at the province level in mainland China, 2011-2018.

PLoS ONE, 2022
Although three monovalent EV-A71 vaccines have been launched in mainland China since 2016, hand, foot, and mouth disease (HFMD) still causes a considerable disease burden in China. Vaccines' use may change the epidemiological characters of HFMD.
Yuanzhe Wu, Tingwei Wang, Mingyi Zhao, Shumin Dong, Shiwen Wang, Jingcheng Shi   +5 more
doaj   +1 more source

Managing hand-foot-mouth disease in children: More of counseling, less of medicines

Journal of Family Medicine and Primary Care
Hand, foot, and mouth disease (HFMD) is a clinical syndrome characterized by a febrile illness, followed by an oral exanthema and a macular, maculopapular, or vesicular rash of the hands, also involving palms, feet, and buttocks caused by enteroviruses ...
M.M.A. Faridi, Sakshi Kapoor, Snigdha, Shrish Bhatnagar   +3 more
doaj   +1 more source

Incidence, aetiology, and serotype spectrum analysis of adult hand, foot, and mouth disease patients: A retrospective observational cohort study in northern Zhejiang, China

International Journal of Infectious Diseases, 2019
Background: Hand, foot, and mouth disease (HFMD) in adults has rarely been reported in the literature, although its clinical significance is underestimated. This study was performed to systematically elucidate the epidemiological characteristics of adult
Linghua Yu, Jin He, Linlin Wang, Huixing Yi   +3 more
doaj   +1 more source