Results 61 to 70 of about 4,110 (164)

The relationship between selenium and viral diseases

Interdisciplinary Medicine, Volume 3, Issue 2, March 2025.
This review describes the application and research progress of selenium in antiviral therapy. Starting from the biological functions of selenium, this paper discusses the association of selenium with a variety of viral diseases and analyzes in depth the antiviral mechanisms of selenium, including its immunomodulatory and antioxidant effects.
Jiali Li, Jia Lai, Yuhui Zeng, Bing Zhu, Yinghua Li   +4 more
wiley   +1 more source

Targeting WDPF domain of Hsp27 achieves a broad spectrum of antiviral

MedComm, Volume 6, Issue 3, March 2025.
Ser78 phosphorylation of Hsp27 plays an important role in Hsp27 nuclear translocation, which induces hnRNP A1 cytosol relocation and further enhances the IRES activity and viral replication mediated by EV‐A71 2Apro. Hsp27‐derived WDPF peptide competitively inhibited Hsp27 phosphorylation on serine 78 to block Hsp27/hnRNP A1 translocation and further ...
Mandi Wu, Wei Li, Houying Leung, Yiran Wang, Qianya Wan, Peiran Chen, Cien Chen, Yichen Li, Xi Yao, Ming‐Liang He   +9 more
wiley   +1 more source

Meteorological factors associated with hand, foot and mouth disease in a Central Highlands province in Viet Nam: an ecological study

Western Pacific Surveillance and Response, 2019
Background: Hand, foot and mouth disease (HFMD) is a public health problem in Viet Nam, and studies have reported seasonal fluctuation in the occurrence of HFMD.
Hau Van Pham, Uyen Thi Ngoc Phan, Anh Nguyen Quynh Pham   +2 more
doaj   +1 more source

In Vitro Discovery of a Therapeutic Lead for HFMD From a Library Screen of Rocaglates/Aglains

Journal of Medical Virology, Volume 97, Issue 2, February 2025.
ABSTRACT The lack of effective antiviral treatments for enteroviruses, including human enterovirus A71 (EV‐A71), have resulted in an immense global healthcare burden associated with hand‐foot‐and‐mouth disease (HFMD). Rocaglates and aglains belong to a family of compounds produced by Aglaia genus plants.
Adrian Oo, Angel Borge, Regina Ching Hua Lee, Cyrill Kafi Salim, Wenyu Wang, Michael Ricca, Deborah Yuhui Fong, Sylvie Alonso, Lauren E. Brown, John A. Porco Jr., Justin Jang Hann Chu   +10 more
wiley   +1 more source

Effect of Climatic Factors on Hand, Foot, and Mouth Disease in South Korea, 2010-2013. [PDF]

PLoS ONE, 2016
Hand, foot, and mouth disease (HFMD) causes characteristic blisters and sores mainly in infants and children, and has been monitored in South Korea through sentinel surveillance since 2009.
Bryan Inho Kim, Hyunok Ki, Sunhee Park, Eunhi Cho, Byung Chul Chun   +4 more
doaj   +1 more source

First Report of Hand, Foot, and Mouth Disease (HFMD) Outbreak in the West Bank, Palestine: Molecular Characterization of Coxsackievirus A16 (CV‐A16)

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2025, Issue 1, 2025.
Introduction: Hand, foot, and mouth disease (HFMD) is a mild self‐limited childhood infectious disease caused by a variety of enteroviruses (EVs). Aim: To investigate the molecular epidemiology of EVs associated with HFMD and their clinical presentation during the HFMD outbreak that occurred in the Jenin district, Palestine, from May to August 2024 ...
Kamal Dumaidi, Amer Al-Jawabreh, Areej Zraiqi, Athar Fashafsha, Ahmad Dumaidi, Marcos Christian Bautista   +5 more
wiley   +1 more source

Comprehensive Review on Viral RNA Extraction Strategies for Enhanced Molecular Diagnostics

Interdisciplinary Perspectives on Infectious Diseases, Volume 2025, Issue 1, 2025.
RNA viruses, characterized by their RNA‐based genomes, have garnered significant concern due to their role in numerous lethal pandemics and remain a significant global health threat. Their predominance among emerging pathogens underscores the need for rapid detection and molecular characterization.
I. Made Artika, Chairin Nisa Ma’roef, Edison Johar, Frilasita Aisyah Yudhaputri, Khin Saw Aye Myint, Suraiya Saleem   +5 more
wiley   +1 more source

Spatio-temporal analysis of the relationship between meteorological factors and hand-foot-mouth disease in Beijing, China

BMC Infectious Diseases, 2018
Background Hand-foot-mouth disease (HFMD) is a common infectious disease in China and occurs mostly in infants and children. Beijing is a densely populated megacity, in which HFMD has been increasing in the last decade.
Lin Tian, Fengchao Liang, Meimei Xu, Lei Jia, Xiaochuan Pan, Archie C. A. Clements   +5 more
doaj   +1 more source

Biological Properties, Health Benefits and Semisynthetic Derivatives of Edible Astraeus Mushrooms (Diplocystidiaceae): A Comprehensive Review

Chemistry &Biodiversity, Volume 21, Issue 12, December 2024.
Abstract Edible Astraeus mushrooms are known for their nutritional and culinary benefits and potential therapeutic properties. However, more investigation and discussion are still needed to understand their mechanisms of action regarding observed biological activities and thorough chemical analysis of bioactive compounds.
Alison T. Ung, Hui Chen
wiley   +1 more source

The Clinical and Epidemiological Study of Children with Hand, Foot, and Mouth Disease in Hunan, China from 2013 to 2017

Scientific Reports, 2019
Hand, foot, and mouth disease (HFMD) is endemic in the Pacific region, especially in mainland China. The case-fatality ratio of HFMD is increasing steadily. Knowledge of the changing epidemiology of HFMD in different regions is necessary for implementing
Jun Qiu, Haipeng Yan, Nianci Cheng, Xiulan Lu, Xia Hu, Lijuan Liang, Zhenghui Xiao, Lihong Tan   +7 more
doaj   +1 more source