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Myocardial Metabolic Reprogramming in HFpEF

Journal of Cardiovascular Translational Research, 2023
Heart failure (HF) caused by structural or functional cardiac abnormalities is a significant cause of morbidity and mortality worldwide. While HF with reduced ejection fraction (HErEF) is well understood, more than half of patients have HF with preserved ejection fraction (HFpEF).
Zihui Zhang   +5 more
openaire   +2 more sources

Sex Differences in HFpEF

Current Treatment Options in Cardiovascular Medicine, 2020
Heart failure with preserved ejection fraction (HFpEF) disproportionately affects women. Though no unifying theory exists to explain this phenomenon, the purpose of this review is to explore the many factors that likely contribute to this female predominance.
Anna C. O’Kelly, Emily S. Lau
openaire   +1 more source

HFpEF treatment: pharmacological therapy

2018
Heart failure with preserved ejection fraction (HFpEF) is a diverse syndrome characterized by signs and symptoms of heart failure with relatively preserved ejection fraction. Despite the established efficacy of numerous classes of drugs and devices in heart failure with reduced ejection fraction, no specific therapy has yet proven to reduce morbidity ...
Maja Cikes, Scott D. Solomon
openaire   +1 more source

Istaroxime in HFpEF

JACC: Heart Failure, 2023
Ryan J. Tedford, Daniel N. Silverman
openaire   +1 more source

Targeting Mitochondria-Inflammation Circuit by β-Hydroxybutyrate Mitigates HFpEF

Circulation Research, 2021
Yan Deng, Qian Li, Xuewen Xu
exaly  

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