Results 41 to 50 of about 34,947 (279)

Resetting the neurohormonal balance in heart failure (HF). the relevance of the natriuretic peptide (NP) system to the clinical management of patients with HF [PDF]

, 2017
The natriuretic peptide (NP) system, which includes atrial natriuretic peptide, B-type natriuretic peptide, and C-type natriuretic peptide, has an important role in cardiovascular homeostasis, promoting a number of physiological effects including ...
Rubattu, Speranza Donatella, Triposkiadis, Filippos   +1 more
core   +2 more sources

Isovolumic relaxation strain imaging is an accurate and sensitive approach for detection of active diastolic dysfunction: A preclinical study

Animal Models and Experimental Medicine, EarlyView.
A modified approach was developed to accurately identify the isovolumetric relaxation time (IVRT) using an apical three‐chamber view. Compared with conventional echocardiography, isovolumic relaxation strain imaging (IVSI) helps to detect the earlier alternations of diastolic function in transverse aortic constriction (TAC) mice.
Jingjing Liang, Juncheng Wang, Jun Cheng, Yanggan Wang   +3 more
wiley   +1 more source

What can we learn from SOCRATES: more questions than answers? [PDF]

, 2017
This editorial refers to ‘Vericiguat in patients with worsening chronic heart failure and preserved ejection fraction: results of the SOluble guanylate Cyclase stimulatoR in heArT failurE patientS with PRESERVED EF (SOCRATES-PRESERVED) Study’, by B ...
Cleland, John G.F., Mueller, Christian
core   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Resistant hypertension in elderly: a clinical manifestation of heart failure with preserved ejection fraction? retrospective single-center analysis

Clinical and Experimental Hypertension, 2019
Background: Resistant hypertension (RHT) is defined as high blood pressure despite three antihypertensive medications one being a diuretic. RHT is a common clinical problem and as a subgroup has not been studied widely. The present study has investigated
Ebru Ipek Turkoglu, Emine Cigdem Kircicegi Cıcekdag   +1 more
doaj   +1 more source

Intravascular Lithotripsy Is Associated With Superior Clinical Outcomes Compared to Atherectomy: A Large‐Scale, Propensity‐Matched Analysis

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Coronary artery disease (CAD) with severe calcification remains a growing challenge in percutaneous coronary intervention (PCI). Atherectomy (ATH) has long been used for plaque modification, whereas intravascular lithotripsy (IVL) has emerged as a promising alternative. Large‐scale comparative data on long‐term outcomes are limited.
Charles D. Miks, Grant K. Ozaki, Chirayu R. Shukla, Vikram Sharma   +3 more
wiley   +1 more source

Tetranectin as a potential biomarker in heart failure with ejection fraction >45%: A prospective cohort study

Romanian Journal of Internal Medicine
Heart failure (HF) with left ventricle ejection fraction (LVEF) >45% lacks reliable biomarkers for risk stratification complicating its management, as it encompasses both heart failure with preserved ejection fraction (HFpEF, LVEF ≥50%) and mildly ...
Vulciu Paula Alexandra, Pilat Luminita, Varga Norberth-Istvan, Dascau Voicu, Popa Calin, Mot Maria-Daniela, Barata Paula Irina, Donath Miklos Imola, Puschita Maria   +8 more
doaj   +1 more source

Patient Perspectives on the Burden of Heart Failure with Preserved Ejection Fraction in a US Commercially Insured and Medicare Advantage Population: A Survey Study

Patient Preference and Adherence, 2023
Chi Nguyen,1 Luke Bamber,2 Vincent J Willey,1 Thomas Evers,2 Thomas P Power,3 Judith J Stephenson1 1HealthCore, Inc., Wilmington, DE, USA; 2Bayer AG, Wuppertal, 42096, Germany; 3AIM Specialty Health, Chicago, IL, USACorrespondence: Chi Nguyen, HealthCore,
Nguyen C, Bamber L, Willey VJ, Evers T, Power TP, Stephenson JJ   +5 more
doaj  

Impact of severe secondary tricuspid regurgitation on rest and exercise hemodynamics of patients with heart failure and a preserved left ventricular ejection fraction

Frontiers in Cardiovascular Medicine, 2023
BackgroundBoth secondary tricuspid regurgitation (STR) and heart failure with preserved ejection fraction (HFpEF) are relevant public health problems in the elderly population, presenting with potential overlaps and sharing similar risk factors. However,
Claudia Baratto, Sergio Caravita, Sergio Caravita, Giorgia Corbetta, Giorgia Corbetta, Davide Soranna, Antonella Zambon, Antonella Zambon, Céline Dewachter, Mara Gavazzoni, Francesca Heilbron, Michele Tomaselli, Noela Radu, Francesco Paolo Perelli, Francesco Paolo Perelli, Giovanni Battista Perego, Jean-Luc Vachiéry, Gianfranco Parati, Gianfranco Parati, Luigi P. Badano, Luigi P. Badano, Denisa Muraru, Denisa Muraru   +22 more
doaj   +1 more source

Association is not causation: treatment effects cannot be estimated from observational data in heart failure [PDF]

, 2018
Aims: Treatment ‘effects’ are often inferred from non-randomized and observational studies. These studies have inherent biases and limitations, which may make therapeutic inferences based on their results unreliable.
Campbell, Ross T., Jhund, Pardeep S., McMurray, John J.V., Petrie, Mark C., Rush, Christopher J.   +4 more
core   +1 more source