Results 81 to 90 of about 5,611,155 (244)

T cells from newly diagnosed multiple sclerosis patients have enhanced responsiveness to CD46 activation

Clinical and Experimental Neuroimmunology, EarlyView.
Abstract Objective To evaluate the responsiveness of T cells from newly diagnosed multiple sclerosis (MS) patients to CD46 co‐stimulation, a membrane co‐factor protein potentially involved in MS pathogenesis. Methods T cells from MS patients and non‐diseased symptomatic controls (SC) were activated in vitro with or without αCD46 antibody co‐stimulation.
Linda Sundvall, Litten S. Rossen, Vivien R. Schack, Bettina Bundgaard, Peter V. Rasmussen, Thor Petersen, Per Höllsberg   +6 more
wiley   +1 more source

High Human Herpesvirus 8 (HHV-8) Prevalence, Clinical Correlates and High Incidence among Recently HIV-1-Infected Subjects in Sao Paulo, Brazil

PLoS ONE, 2009
Background Human herpesvirus 8 (HHV-8) is the etiological agent for Kaposi Sarcoma, which occurs especially in HIV-infected subjects. HHV-8 infection and its clinical correlates have not been well characterized in recently HIV-1-infected subjects ...
M. D. Batista, S. Ferreira, M. M. Sauer, H. Tomiyama, M. T. Giret, C. Pannuti, R. Diaz, E. Sabino, E. Kallás   +8 more
semanticscholar   +1 more source

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

Cell Proliferation, EarlyView.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan, Zhou Chen, Yuhua Zhang, Wenjie Sun, Lifei Li, Xia Huang   +5 more
wiley   +1 more source

Multicentric Castleman disease is associated with polyfunctional effector memory HHV-8-specific CD8+ T cells.

Blood, 2008
Multicentric Castleman disease (MCD) is a devastating human herpesvirus 8 (HHV-8)-related lymphoproliferative disorder that occurs in immunocompromised persons.
A. Guihot, É. Oksenhendler, L. Galicier, A. Marcelin, L. Papagno, A. Bedin, F. Agbalika, N. Dupin, J. Cadranel, B. Autran, G. Carcelain   +10 more
semanticscholar   +1 more source

Is Kaposi sarcoma a novel comorbidity of cutaneous lymphoma? A systematic review of the literature

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 4, Page 467-477, April 2025.
Summary Background and Objectives Patients with cutaneous lymphomas (CL) are at an increased risk of developing secondary malignancies. This study aimed to assess the frequency of association between CL and Kaposi sarcoma (KS) and to identify factors that may promote the co‐occurrence of these two diseases.
Rose K. C. Moritz, Julia Huynh, Gabriela Poch, Robert Sabat, Max Schlaak, Gabor Dobos   +5 more
wiley   +1 more source

Primary gamma-herpesviral infection in Zambian children

BMC Infectious Diseases, 2010
Background HHV-8 is closely related to Epstein-Barr virus (EBV), but the clinical presentations of these two infections in early childhood are not well understood. Also, it is not known whether infection by one virus correlates with another.
Mitchell Charles D, Kankasa Chipepo, Crabtree Kay L, Brayfield Brad P, Minhas Veenu, Wood Charles   +5 more
doaj   +1 more source

Torque teno virus as a marker of immune status in immunocompromised patients: A systematic review

European Journal of Clinical Investigation, EarlyView.
Abstract Background Torque teno virus (TTV) is not known to cause disease in humans; however, chronic inflammatory conditions and immunosuppression states can favour TTV replication. This study aimed to verify the effectiveness of TTV as an immune biomarker.
Janaina B. Medina, Fábio França Vieira e Silva, Rafael Antônio Velôso Caixeta, Bruna de Oliveira Rech, Alba Perez‐Jardón, María Elena Padín‐Iruegas, Mario Pérez‐Sayáns, Paulo Henrique Braz‐Silva, Karem L. Ortega   +8 more
wiley   +1 more source

Relación entre el virus humano herpes 8 y el sarcoma de Kaposi en pacientes positivos y negativos para el VIH Relationship between human herpes virus 8 and Kaposi sarcomain HIV positive and negative patients

Infectio, 2007
Introducción. Parece existir una relación de causalidad entre la infección por el virus humano herpes 8 ( human Herpesvirus 8, HHV-8) y el desarrollo de sarcoma de Kaposi, especialmente en la población positiva para virus de inmunodeficiencia humana (VIH)
BEATRIZ OROZCO, LUZ MARINA GÓMEZ, SANTIAGO ESTRADA, BLANCA NELLY RESTREPO, JUAN CARLOS CATAÑO   +4 more
doaj  

Seroprevalence and Risk Factors for Human Herpesvirus 8 Infection, Rural Egypt

Emerging Infectious Diseases, 2008
To determine whether human herpesvirus 8 (HHV-8) is associated with schistosomal and hepatitis C virus infections in Egypt, we surveyed 965 rural household participants who had been tested for HHV-8 and schistosomal infection (seroprevalence 14.2% and 68.
Sam M. Mbulaiteye, Ruth M. Pfeiffer, Bryan Dolan, Victor C.W. Tsang, John Noh, Nabiel N.H. Mikhail, Mohamed Abdel-Hamid, Mohamed Hashem, Denise Whitby, G. Thomas Strickland, James J. Goedert   +10 more
doaj   +1 more source

Seroprevalence of HHV-8, CMV, and EBV among the general population in Ghana, West Africa

BMC Infectious Diseases, 2008
BackgroundHuman herpesvirus 8 (HHV-8), cytomegalovirus (CMV) and Epstein-Barr virus (EBV) are prevalent in Africa, but less common elsewhere and the modes of transmission are still subject to debate.
A. Adjei, H. Armah, F. Gbagbo, I. Boamah, C. Adu-Gyamfi, I. Asare   +5 more
semanticscholar   +1 more source