Results 201 to 210 of about 52,256 (258)

Transforming Musculoskeletal Disorder Management With Multimodal AI Platform for Early Diagnosis, Self‐Screening, and Personalized Care

Med Research, EarlyView.
We developed a multimodal large language model‐enabled framework for the early detection, self‐screening, and personalized management of major musculoskeletal disorders, including osteoarthritis (OA), rheumatoid arthritis (RA), and osteoporosis (OP).
Pengyuan Xu, Guang Yang, Ge Zhang, Yafang Zhao, Pu Wan, Guiyun Zhou, Mengjie Jiang, Yixin Zhang, Zhaoyang Wang, Yichen Dai, Xiqing Zhao, Ziliang Fu, Ziyu Zheng, Ziyun Xu, Ruisi Dong, Xiaojie Xia, Duo Zhang, Yisheng He, Michael Moran, Qiguang Wang, Tim Woodfield, Khoon Lim, Tiantian Kong, Junnan Tang, Kang Tian, Kai Zhou, Hao Chi, Pengpeng Zhang, Jianhua Yang, Mingliang Zhang, Moyan Li, Yuan Cheng, Xiaolin Cui   +32 more
wiley   +1 more source

Information Design for Early‐Stage Dose‐Finding Trials

Naval Research Logistics (NRL), EarlyView.
ABSTRACT To enhance enrollment rates in early‐stage dose‐finding clinical trials, we propose an information design approach, where the clinical investigator (CI) commits to an information releasing mechanism (IRM) based on the treatment's uncertain efficacy and toxicity to encourage patients to participate in the trial.
Amin Khademi, Ningyuan Chen
wiley   +1 more source

Musculoskeletal Outcomes of Glucagon‐Like Peptide‐1 Receptor Agonists Versus Other Antiobesity Agents in Nondiabetic Adults

Obesity, EarlyView.
ABSTRACT Objective This study aimed to evaluate the association of glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) with risks of osteoporosis, major osteoporotic fractures, and degenerative musculoskeletal disorders in nondiabetic adults with obesity compared with other obesity medications.
Jie‐Syuan Wu, Lee‐Yuan Lin, Jia‐Wei Sun, Wei‐Ting Yu, Fara Silvia Yuliani, Shyh‐Hsiang Lin   +5 more
wiley   +1 more source

Hidden blood loss of minimally invasive transforaminal lumbar interbody fusion of lumbar degenerative diseases in patients with osteoporosis: a retrospective study. [PDF]

J Orthop Surg Res
Lin S, Liu S, Li Y, Yan Y, Ye H.
europepmc   +1 more source

The magnitude and economic replacement value of wild meat obtained from ‘recreational’ big game hunting in the United States

People and Nature, EarlyView.
Abstract Meat production has notable benefits for food security, nutrition and various production economies, but has elicited substantial negative environmental impacts. Recreational hunting provides an alternative to agricultural meat production for over 24 million hunters worldwide.
Shane P. Mahoney, Richard D. Honor
wiley   +1 more source

Optical mapping reveals a higher level of large‐scale structural variants in a family with paternally transmitted myotonic dystrophy and independent Parkinson's disease

The Journal of Pathology, EarlyView.
Abstract Myotonic dystrophy type 1 (DM1) is a clinically challenging multisystem neuromuscular hereditary disorder, with generational increase in severity and earlier age at onset. It is caused by an unstable cytosine‐thymine‐guanine repeat expansion at the DMPK locus, accompanied by associated genetic and epigenetic modifications.
Md Mehedi Hasan, Jenna Craddock, Tingting Gong, Ruth J Lyons, Igor Stevanovski, Sanjog R Chintalaphani, Ira W Deveson, Weerachai Jaratlerdsiri, Kishore R Kumar, Vanessa M Hayes   +9 more
wiley   +1 more source

Mild Malnutrition in Children Aged 6–24 Months and Related Influencing Factors: Research From an Outpatient Clinic of Pediatric Health Care

Pediatric Discovery, EarlyView.
ABSTRACT Mild malnutrition in infants and young children is an early stage of nutritional deficiency characterized by a slight reduction in nutritional reserves and mild impairment of physiological functions but no obvious clinical symptoms or severe growth retardation. Parents often overlook this condition because typical signs are absent.
Menghua Yin, Qian Li, Rumeng Yu, Mengxuan Zhou, Wenxiu Wu, Li Song   +5 more
wiley   +1 more source

SPROUTS_DB: An Implemented Database of Contaminants for Extracellular Vesicle Proteomics Studies

PROTEOMICS, EarlyView.
ABSTRACT Current proteomics techniques allow rapid identification and quantification of proteins within any given biological source. However, LC–MS/MS proteomics is vulnerable to laboratory and sample‐associated contaminants. Therefore, accurate identification and annotation of such contaminants is crucial for development of reliable databases ...
Maria Gaetana Giovanna Pittalà, Loredana Leggio, Greta Paternò, Elena Giusto, Laura Civiero, Vincenzo Cunsolo, Silvia Vivarelli, Antonella Di Francesco, Emanuele Alpi, Nunzio Iraci, Rosaria Saletti   +10 more
wiley   +1 more source

Hidden blood loss in unilateral open-door cervical laminoplasty for multilevel cervical spondylotic myelopathy. [PDF]

Jt Dis Relat Surg
Yang Y, Wang F.
europepmc   +1 more source

The efficacy and safety of acupuncture compared to Western medicine in patients with nonalcoholic fatty liver disease: A systematic review and meta‐analysis

Precision Medical Sciences, EarlyView.
This study conducted a systematic review and meta‐analysis of randomized controlled trials (RCTs) to investigate whether acupuncture treatment is more beneficial than Western medicine treatment for patients with nonalcoholic fatty liver disease. The results showed that acupuncture was significantly superior to Western medicine in terms of clinical ...
Bin Yu, Yuxin Zhu, Yue Tong, Haomeng Zhang, Xiuli Lu, Hui He, Shuang Liang, Fuyu Xue, Haipeng Huang   +8 more
wiley   +1 more source