ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li +25 more
wiley +1 more source
Uncovering the hidden costs of free tuberculosis care: economic narratives of informal treatment supporters in rural Ghana. [PDF]
Bio RB, Azaare J, Laar RA, Titiati A.
europepmc +1 more source
A general health economics review of the hidden costs involved in discharging coeliac patients from hospital-based specialty clinics to community-based management. [PDF]
Greenham O, Johnson L, Johnson M.
europepmc +1 more source
Forecasting Root Rot Disease through Predictive Microbial Functional Profiling
Predicting soil‐borne disease moves beyond observation with a framework that elevates microbial functional genes into reliable forecasting biomarkers. By coupling targeted qPCR assays for core stress‐response genes with machine learning, this method detects root rot risks in pre‐symptomatic soils with over 80% accuracy.
Chuan You +11 more
wiley +1 more source
Fertility in Fevered Planet, Hidden Costs of Global Warming. [PDF]
Reza Sadeghi M.
europepmc +1 more source
A series of photo‐responsive polymers are prepared by a facile one‐pot in situ synthesis strategy, where RTP modules and photochromic units are systematically integrated into one polymer system. The triplet‐singlet Förster resonance energy transfer (TS‐FRET) between the donor and acceptor enables the material to exhibit time‐dependent phosphorescence ...
Ziyi Bai +5 more
wiley +1 more source
Hidden costs of unaffordable housing: Exploring the multidimensional and intersecting health effects on Black Americans. [PDF]
Bradley ELP +4 more
europepmc +1 more source
Parametric Cognitive Load Reveals Hidden Costs in the Neural Processing of Perfectly Intelligible Degraded Speech. [PDF]
Ritz H, Wild CJ, Johnsrude IS.
europepmc +1 more source
This review examines the evolution of bioprinting toward minimally invasive in situ strategies for internal organ regeneration. It defines the technological roadmap from handheld systems to advanced minimally invasive bioprinting platforms, positioning soft robotics as a core enabler.
Duc Tu Vu +9 more
wiley +1 more source

