Results 141 to 150 of about 53,114 (263)

From patient to tumor organoid: Culture protocol choice controls glioblastoma tumor architecture and identity

Brain Pathology, EarlyView.
How glioblastoma organoids are made shapes what they become. Fragment‐based cultures preserve extracellular matrix networks, cellular diversity, and primary tumor identity, whereas dissociation‐based cultures shift toward growth‐adapted states and simplified microenvironments. Abstract Patient‐derived tumor organoids are widely used in cancer research,
Jana Slovackova, Ondrej Bernatik, Katarina Cimborova, Martin Barak, Michal Hendrych, Karolina Kocourkova, Marie Sulcova, Jaroslav Olha, Katerina Amruz Cerna, Zdenek Hodny, Radim Jancalek, Dasa Bohaciakova   +11 more
wiley   +1 more source

Joint Bayesian Hidden Markov Model With Subject-Specific Transitions for Wearable Sensor Data. [PDF]

Stat Med
Fei W, Miao Z, Xu T, Wang Y.
europepmc   +1 more source

Decoding functional specialization in G protein‐coupled receptors (GPCRs) through evolution‐guided residue profiling

British Journal of Pharmacology, EarlyView.
Background and Purpose G protein‐coupled receptors (GPCRs) are integral membrane proteins that mediate physiological processes by enabling cells to detect and respond to diverse stimuli. Although many subfamily‐specific functional hotspots have been described, the family‐wide determinants of common and subfamily‐specific functions remain incomplete ...
Berkay Selçuk, Gunnar Schulte, Igor B. Zhulin, Ogün Adebali   +3 more
wiley   +1 more source

Dynamic Brain State Alterations in Narcolepsy: A Hidden Markov Model Approach to Thalamocortical Instability and Symptom-Specific Neural Correlates. [PDF]

Brain Behav
Li W, Jia L, Wang X, Zhao Y, Li Z, Geng Z.   +5 more
europepmc   +1 more source

Under the cover of darkness: Foraging behaviour increases on cloudy, new moon nights in a pelagic seabird

Ibis, EarlyView.
While many visual predators feed exclusively during the day, others exploit foraging opportunities at night, although the efficiency with which they do so is strongly influenced by ambient light levels. We investigated the influence of variation in nocturnal light on the foraging behaviour of a small pelagic seabird, the European Storm‐petrel ...
Darren Wilkinson, Adam Kane, Mark Jessopp, John L. Quinn   +3 more
wiley   +1 more source

Adaptive Phoneme State Learning Architecture for Enhanced Speech Recognition Using Backpropagation Neural Network and Hidden Markov Model. [PDF]

F1000Res
Siddalingappa R, S D, Savitha M, P K, Stella Mary I P, Gornale S, B A L, Li K, Wen Goh K.   +8 more
europepmc   +1 more source

Measuring the Stringency of Building Height Regulations

International Economic Review, EarlyView.
ABSTRACT This study proposes a novel methodology to measure the stringency of building height regulations. This measure gauges the difference in building heights with and without regulations. The primary challenge is to recover unobserved building heights in the absence of regulations.
Yusuke Adachi
wiley   +1 more source

Assessment of goose-beaked whale responses to mid-frequency active sonar using a hierarchical hidden Markov model. [PDF]

Mov Ecol
DeRuiter SL, Falcone EA, Coates SN, Rone BK, Sweeney DA, Dolan KA, Jarvis SM, Andrews RD, Watwood SL, Schorr GS.   +9 more
europepmc   +1 more source

Cryptic diversity and recent diversification in the Pyrrhulina australis species complex (Characiformes, Lebiasinidae) revealed by mitochondrial DNA

Journal of Fish Biology, EarlyView.
Abstract Pyrrhulina australis Eigenmann & Kennedy, 1903, is widely distributed across the main hydrographic basins of South America. The taxonomic integrity of this species is nevertheless challenged by the lack of clear diagnostic characters, its marked geographic variation and the morphological overlap with its congeners. In this context, the present
Taina Barbosa De Souza, Daniela Cristina Ferreira, Hugmar Pains Da Silva, Carolina B. Machado, Claudio Oliveira, André L. Netto‐Ferreira, Paulo C. Venere   +6 more
wiley   +1 more source

State-specific disruptions of dynamic functional connectivity in young migraine without aura: a hidden Markov model approach. [PDF]

Front Neurosci
Xu C, Zhan S, Tan W, Cheng JM, Gong S, Lu S, Wang H, Liu F, Jiang S, Wang W, Yang Y.   +10 more
europepmc   +1 more source