Results 51 to 60 of about 11,461 (257)

Pyoderma Gangrenosum: A Retrospective Cohort Study of Comorbidities and Therapies in Over 65,000 Patients in the TriNetX Database

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis associated with systemic inflammatory diseases and malignancy. Although biologic therapies demonstrate efficacy in PG, the extent of their real‐world use remains incompletely characterized.
Rhiannon Grange, Tara Sholji, Marra Aghajani, Cindy Kok, John Frew   +4 more
wiley   +1 more source

Paradoxical Alopecia Areata Induced by IL‐17 and IL‐23 Inhibitors: A Systematic Review

JEADV Clinical Practice, EarlyView.
This systematic review identifies consistent clinical patterns of alopecia areata associated with IL‐17 and IL‐23 inhibitors, most frequently involving secukinumab and ustekinumab. Disease severity varied widely, and management often required biologic discontinuation or therapeutic switching.
Isabella Kamholtz, Simonetta I. Gaumond, Joaquin J. Jimenez   +2 more
wiley   +1 more source

Hidradenitis Suppurativa in Pediatric Patients.

, 2023
Hidradenitis suppurativa is a chronic inflammatory skin disorder primarily affecting apocrine gland-bearing areas, including the axillae, groin, and buttocks. It is reported in up to 2% of Western populations and with increasing incidence in children and
Zaenglein, Andrea L, Cotton, Colleen H, Chen, Stella X, Lara-Corrales, Irene, Hussain, Sadaf H   +4 more
core  

Therapeutic Challenges in Managing Coexisting Hidradenitis Suppurativa and Squamous Cell Carcinoma: A Clinical Case Study

JEADV Clinical Practice, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder affecting intertriginous areas. Long‐standing HS can undergo malignant transformation into squamous cell carcinoma (SCC), particularly in the perineal and gluteal regions. We report a 54‐year‐old man with severe, treatment‐refractory HS complicated by an aggressive verrucous
Michael Zolotas, Tereza Jakovljevicova, Kamran Ghoreschi, Kerstin Kusch, Marisa Klemp, Robert Sabat, Georgios Kokolakis   +6 more
wiley   +1 more source

Hidradenitis suppurativa blood proteome.

, 2018
Hidradenitis suppurativa blood proteome.
Afsaneh Alavi (5196227), Gregory Schultz (75606), Niroshana Anandasabapathy (2732299), Mayte Suárez-Fariñas (27734), Lauren K. Hoffman (5802338), Michael D. Howell (546920), Lewis E. Tomalin (5802341), Michelle A. Lowes (115722)   +7 more
core   +1 more source

1726‐nm Laser Treatment of Hidradenitis Suppurativa Tunnels in a Pediatric Skin of Color Patient: Clinical and Ultrasound Outcomes

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives To evaluate the safety, tolerability, and early clinical and ultrasound effects of a 1726‐nm laser for hidradenitis suppurativa (HS) tunnels in a pediatric patient with skin of color. Materials and Methods A 16‐year‐old female (Fitzpatrick skin type VI) with moderate HS and bilateral axillary draining tunnels underwent 4 monthly ...
Emilee M. Dreifus, Gabriela E. Beraja, Aditi Chokshi, Alyx Rosen, Ariel E. Eber   +4 more
wiley   +1 more source

Prevalence and Characteristics of Hidradenitis Suppurativa in the Northern Finland Birth Cohort 1986 Study: A Cross-sectional Study of 2,775 Subjects

Acta Dermato-Venereologica
A negative stigmatization related to hidradenitis suppurativa may prevent patients from seeking care. Thus, a large proportion of patients with hidradenitis suppurativa may be missing from studies based on hospital data.
Suvi-Päivikki Sinikumpu, Jari Jokelainen, Laura Huilaja   +2 more
doaj   +1 more source

Hidradenitis suppurativa in AIDS

Indian Journal of Sexually Transmitted Diseases and AIDS, 2010
Hidradenitis suppurativa (HS) is a disorder of the terminal follicular epithelium in the apocrine gland-bearing skin, characterized by comedo-like follicular occlusion, chronic relapsing inflammation, mucopurulent discharge, and progressive scarring.
Khambhati, Ravi, Singhal, Priyanka, Marfatia, Y. S.   +2 more
openaire   +3 more sources

Spatially Profiling Trace Cytokine Signatures From Microscopically Derived Skin Samples to Probe Skin Disease Inflammation

Small Methods, EarlyView.
Inflammatory skin diseases are driven by immune dysregulation and cytokine imbalance. A challenge persists in profiling cytokines in microscopically derived biopsy skin samples due to low protein content. This study introduces a digital SERS immunoassay to simultaneously detect IL‐17A, IL‐22, IL‐23, and TNF at trace concentrations as low as 104 aM. The
Aditya Krishnakumar, Zhen Zhang, Courtney Vedelago, Timothy J. Liu, Yung‐Ching Kao, H. Peter Soyer, Mitchell S. Stark, Snehlata Kumari, Matt Trau, Alain Wuethrich   +9 more
wiley   +1 more source

Hidradenitis suppurativa skin transcriptome.

, 2018
Hidradenitis suppurativa skin transcriptome.
Afsaneh Alavi (5196227), Gregory Schultz (75606), Niroshana Anandasabapathy (2732299), Mayte Suárez-Fariñas (27734), Lauren K. Hoffman (5802338), Michael D. Howell (546920), Lewis E. Tomalin (5802341), Michelle A. Lowes (115722)   +7 more
core   +1 more source