Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes +14 more
wiley +1 more source
Hierarchical Clustering via Single and Complete Linkage Using Fully Homomorphic Encryption. [PDF]
Sokhonn L, Park YS, Lee MK.
europepmc +1 more source
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen +19 more
wiley +1 more source
Energy efficient hierarchical clustering based dynamic data fusion algorithm for wireless sensor networks in smart agriculture. [PDF]
Srinivasan D +3 more
europepmc +1 more source
Schematic showing a stretchable triboelectric nanogenerator based on interlocked wavy architectures that uses EGaIn microflower‐embedded PVDF‐TrFE and Nylon‐6 nanofiber membranes. The multi‐petaled, electron‐rich EGaIn microflowers enhance interfacial polarization and capacitance, while the interlocked wavy architecture enlarges the effective contact ...
Qianqian Xu +12 more
wiley +1 more source
Characterisation of colorectal cancer by hierarchical clustering analyses for five stroma-related markers. [PDF]
Ito S +15 more
europepmc +1 more source
An Integrated NLP‐ML Framework for Property Prediction and Design of Steels
This study presents a data‐driven framework that uses language‐processing techniques to interpret steel processing descriptions and machine‐learning models to predict mechanical properties. By organising complex process histories into meaningful groups and enabling rapid property forecasts, the work supports faster, more informed steel design through ...
Kiran Devraju +5 more
wiley +1 more source
Influence of Sleep Quality on Recovery and Performance in Endurance and Ultra-Endurance Runners: Sex Differences Identified Through Hierarchical Clustering. [PDF]
Matos JP +7 more
europepmc +1 more source
This review comprehensively summarizes the atomic defects in TMDs for their applications in sustainable energy storage devices, along with the latest progress in ML methodologies for high‐throughput TEM data analysis, offering insights on how ML‐empowered microscopy facilitates bridging structure–property correlation and inspires knowledge for precise ...
Zheng Luo +6 more
wiley +1 more source
Text summarization for pharmaceutical sciences using hierarchical clustering with a weighted evaluation methodology. [PDF]
Dalal A +6 more
europepmc +1 more source

