Results 71 to 80 of about 1,195,838 (307)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Examination of Clustering in Eutectic Microstrcture
Archives of Metallurgy and Materials, 2017 The eutectic microstructures are complex microstructures and a hard work to describe it with few numbers. The eutectics builds up eutectic cells. In the cells the phases are clustered.
Bortnyik K., Barkóczy P.
doaj +1 more source
Threshold-Based Hierarchical Clustering for Person Re-Identification
Entropy, 2021 Unsupervised domain adaptation is a challenging task in person re-identification (re-ID). Recently, cluster-based methods achieve good performance; clustering and training are two important phases in these methods.
Minhui Hu +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
The clustering of galaxies in hierarchical galaxy formation models [PDF]
, 2010 Galaxy clustering encodes information about the values of cosmological parameters and also about the physical processes behind galaxy formation and evolution. The GALFORM semi-analytical model is the theoretical approach we used to model galaxy formation.
KIM, HAN,SIK, Kim, Han Sik
core
Hierarchical Hexagonal Clustering and Indexing [PDF]
Symmetry, 2019 Space-filling curves (SFCs) represent an efficient and straightforward method for sparse-space indexing to transform an n-dimensional space into a one-dimensional representation. This is often applied for multidimensional point indexing which brings a better perspective for data analysis, visualization and queries.
Vojtech Uher +4 more
openaire +4 more sources
KomputikaDalam menghadapi era transformasi digital, masih terjadi ketimpangan pada kondisi keterampilan, akses dan fasilitas teknologi informasi dan komunikasi di Indonesia.
Rahma watin +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Interactive interpretation of hierarchical clustering [PDF]
Intelligent Data Analysis, 1997 Automatic clustering methods are part of data mining methods. They aim at building clusters of items so that similar items fall into the same cluster while unsimilar items fall into separate clusters. A particular class of clustering methods are hierarchical ones where recursive clusters are formed to grow a binary tree representing an approximation of
Eric Boudaillier, Georges Hébrail
openaire +3 more sources