Advanced Science, EarlyView.SPARK decodes structure‐property relationships in anion exchange membranes (AEMs) via a chemically informed dual‐channel graph attention network (DEGAT) that explicitly captures microphase separation. It outputs five‐level grades for hydroxide conductivity and alkaline stability and highlights relevant key structural units, enabling robust pre ...
Wanting Chen +6 more
wiley +1 more source
A Combined Transcriptomic and Machine Learning Study Reveals PAX8 as a Promising Diagnostic Biomarker in Endometriosis. [PDF]
Hum MutatZhu X +5 more
europepmc +1 more source
The Polymers of Life: Exploring Cellular Function Through Polymer Concepts
Advanced Science, EarlyView.Biomolecular phase separation reveals that a hidden layer of cellular organization is governed by the principles of polymer science. This review bridges polymer physics and cell biology, offering a primer on fundamental concepts, proposing a framework for interrogating cellular function, and synthesizing biophysical methods for decoding macromolecular ...
Mark Chen, Ashutosh Chilkoti
wiley +1 more source
Microbial Odorant Detection Guides Drosophila Parasitoids Seeking Hosts in Fermenting Fruits
Advanced Science, EarlyView.Yeast microbes in fermenting fruits attract both host flies and their parasitoid wasps. Female Leptopilina boulardi detect yeast‐emitted ethyl esters via two olfactory receptors, LbouOR167 and LbouOR136. A conserved residue, Leu159, is critical for binding these compounds, enabling female wasps to locate host‐rich habitats.
Yueqi Lu +11 more
wiley +1 more source
De novo functional protein sequence generation: overcoming data scarcity through regeneration and large language models. [PDF]
Brief BioinformRen C, He D, Huang J.
europepmc +1 more source
Advanced Science, EarlyView.Hierarchical PP–LSR107–BaTiO3 nanocomposite films are fabricated by one‐step extrusion and stretching for roll‐to‐roll manufacture, combining high energy storage and processing flexibility. LSR107 surrounds BaTiO3‐rich regions, locating amorphous PP, decreasing defects, and introducing deep traps that homogenize the electric field and suppress charge ...
Yi Gao +14 more
wiley +1 more source
Pain, sleep, fatigue, and health-related quality of life in pediatric sickle cell disease: a serial multiple mediator analysis. [PDF]
Front Pain Res (Lausanne)Varni JW.
europepmc +1 more source
Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair
Advanced Science, EarlyView.Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li +9 more
wiley +1 more source
Bayesian Analysis of Postoperative Complication Risk Associated With Preoperative Exposure to Fine Particulate Matter: A Single-Center Cohort Study. [PDF]
Acta Anaesthesiol ScandPearson JF +13 more
europepmc +1 more source