Results 201 to 210 of about 974,133 (275)

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Innovative statistical method for longitudinal and hierarchical data modeling: the GMEXGBoost method. [PDF]

BMC Med Res Methodol
Asadi F, Homayounfar R, Mehrali Y, Masci C, Zayeri F.   +4 more
europepmc   +1 more source

Recent Progress on Flexible Multimodal Sensors: Decoupling Strategies, Fabrication and Applications

Advanced Materials, EarlyView.
In this review, we establish a tripartite decoupling framework for flexible multimodal sensors, which elucidates the underlying principles of signal crosstalk and their solutions through material design, structural engineering, and AI algorithms. We also demonstrate its potential applications across environmental monitoring, health monitoring, human ...
Tao Wu, Yu‐Tao Li, Luyu Zhao, Yi Zhang, Zhaojie Zhang, Jian Yuan, Yiwen Wu, Anqi Che, Yuanxiao Ma, Yang Chai, Yeliang Wang   +10 more
wiley   +1 more source

Hierarchical Mechanistic Modeling of Complex Toxicity Endpoints from Public Concentration-Response Data. [PDF]

Environ Sci Technol
Chung E, Russo DP, Aleksunes LM, Warner GR, Zhu H.   +4 more
europepmc   +1 more source

Ultra‐Sensitive Nanofiber‐Based Triboelectric Nanogenerator for Energy Harvesting and Self‐Powered Sensing

Advanced Materials, EarlyView.
A multidimensional molecular strategy optimizes the tribonegative layer by electrospinning PVDF‐HFP for dipole alignment and crystallinity, followed by 2D borophene doping to enhance conductivity and charge trapping. Integrated with Nylon‐66 nanofibers, the composite device delivers a record sensitivity of 53.8 ± 1.2 V kPa−1 at 3 Hz, enabling ultra ...
Sajib Roy, Bhaskar Dudem, Md Delowar Hussain, Vlad Stolojan, Seyedeh Sadrieh Emadian, Satheesh Krishnamurthy, Jae Sung Yun, S. Ravi P. Silva   +7 more
wiley   +1 more source

Isometric representations in neural networks improve robustness. [PDF]

Sci Rep
Beshkov K, Verhellen J, Lepperød ME.
europepmc   +1 more source

Bio‐Inspired Hierarchical Nanoreactor With Hetero‐Coordinated Fe–P–Co Bridges for Whole‐Pathway‐Regulated Electrocatalytic Oxygen Reduction

Advanced Materials, EarlyView.
A bioinspired Co‐doped Fe2P on N‐doped carbon with a hierarchical eucalyptus‐like nanoarchitecture is engineered to regulate oxygen across the entire electrochemical pathway, achieving a half‐wave potential of 0.938 V vs. RHE, sustaining 373 h of discharge in Al‐air batteries, and delivering an energy density of 3487 Wh/kg.
Qiaoling Xu, Lei Zhang, Xiayu Li, Weihang Xu, Linyi Ren, Mai Xu, Yingtang Zhou, Hermenegildo Garcia   +7 more
wiley   +1 more source

Phage evolutionary relationships emerge from protein language model-based proteome representation. [PDF]

NAR Genom Bioinform
Panigrahi S, Ansaldi M, Ginet N.
europepmc   +1 more source

A Mechanistic Study of Bio‐Based Nanotemplated Carbon Nanofibers Derived From Water Processable Lignin Blends for Sustainable Energy Storage Applications

Advanced Materials, EarlyView.
As‐spun carbon materials produced from Lignosulfonate, gelatin, and alginate, selected for water solubility, and ability to produce templated sustainable carbon nanostructures. Gelatin and alginate are sacrificial during thermal processing, allowing the production of engineered high surface area nanostructures, which are further characterized for ...
Judith Miralda‐Jalle, Jamal El Haskouri, Shayon Bhattacharya, Anne Beaucamp, Tadhg Kennedy, Mario Culebras, Maurice N. Collins   +6 more
wiley   +1 more source

Tree-Guided Transformer for Sensor-Based Ecological Image Feature Extraction and Multitarget Recognition in Agricultural Systems. [PDF]

Sensors (Basel)
Sun Y, Huang Z, Yang L, Wang Z, Ruan M, Suo J, Yan S.   +6 more
europepmc   +1 more source