Results 51 to 60 of about 337,499 (266)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

TWO-LEVEL HIERARCHICAL COORDINATION QUEUING METHOD FOR TELECOMMUNICATION NETWORK NODES [PDF]

Научно-технический вестник информационных технологий, механики и оптики, 2014
The paper presents hierarchical coordination queuing method. Within the proposed method a queuing problem has been reduced to optimization problem solving that was presented as two-level hierarchical structure.
M. V. Semenyaka
doaj  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

General Chart of Accounts and its Improvement

Учёт. Анализ. Аудит, 2019
Introduction, Purpose. Accounts play a crucial role in modern accounting systems of all countries. They provide the most complete and reliable information both for generating financial statements and making the best educated management decisions. The new
Vasilii Vasil’evich Shcherbatyuk
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Forms of vertical segregation in the contemporary city of Athens

European Journal of Geography
Vertical social segregation as a separation of different social groups in apartment buildings is a phenomenon that mainly appears in the cities of Southern Europe and in some cities of Western and Central Europe.
Nikolina Myofa
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Accounting for clustering for self-reported outcomes in the design and analysis of population-based surveys: A case study of estimation of prevalence of epilepsy in Nairobi, Kenya

Frontiers in Research Metrics and Analytics
Population-based surveys are common for estimation of important public health metrics such as prevalence. Often, survey data tend to have a hierarchical structure where households are clustered within villages or sites and interviewers are assigned ...
Daniel M. Mwanga, Daniel M. Mwanga, Isaac C. Kipchirchir, George O. Muhua, Charles R. Newton, Charles R. Newton, Damazo T. Kadengye   +6 more
doaj   +1 more source

Charge‐transfer‐regulated bimetal ferrocene‐based organic frameworks for promoting electrocatalytic oxygen evolution

Carbon Energy, 2023
The ferrocene (Fc)‐based metal–organic frameworks (MOFs) are regarded as compelling platforms for the construction of efficient and robust oxygen evolution reaction (OER) electrocatalysts due to their superior conductivity and flexible electronic ...
Jinsong Hu, Qiaoling Xu, Xiaoyu Wang, Xinhua Huang, Chunhui Zhou, Ying Ye, Lei Zhang, Huan Pang   +7 more
doaj   +1 more source