Results 11 to 20 of about 349,418 (192)

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

Molecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda, Marina Reguero, Vanesa Abón, Marta Puyol   +3 more
wiley   +1 more source

The Big Five, Type A Personality, and Psychological Well-Being [PDF]

, 2018
The aim of this research was to investigate how the Big Five and Type A personality variables relate to psychological well-being. Additionally, the study examined the effect of age on psychological well-being.
Hicks, Richard E., Mehta, Yukti
core   +1 more source

The Polish adaptation of the Five-Factor Obsessive-Compulsive Inventory – Short Form (FFOCI-SF): A preliminary study [PDF]

, 2019
Background The Five-Factor Obsessive-Compulsive Inventory – Short Form (FFOCI-SF) is an instrument used to measure obsessive-compulsive personality disorder, which is one of the most widespread personality disorders.
Cieciuch, Jan, Kłosowski, Marcin, Strus, Włodzimierz   +2 more
core   +1 more source

Identifying network communities with a high resolution

, 2007
Community structure is an important property of complex networks. An automatic discovery of such structure is a fundamental task in many disciplines, including sociology, biology, engineering, and computer science.
A. Y. Ng, C. Elkan, D. Hand, G. W. Flake, J. Ruan, J. Ruan, Jianhua Ruan, L. Danon, L. Danon, P. N. Tan, P. O. Fjällström, S. White, Weixiong Zhang   +12 more
core   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Matching model of flow table for networked big data

, 2020
Networking for big data has to be intelligent because it will adjust data transmission requirements adaptively during data splitting and merging. Software-defined networking (SDN) provides a workable and practical paradigm for designing more efficient ...
AR Curtis, BSP Lin, D Yin, T Dave, Y Jarraya   +4 more
core   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

The construct validity of the Dutch personality inventory for DSM-5 personality disorders (PID-5) in a clinical sample [PDF]

, 2015
The factor structure and the convergent validity of the Personality Inventory for DSM-5 (PID-5), a self-report questionnaire designed to measure personality pathology as advocated in the fifth edition, Section III of Diagnostic and Statistical Manual of ...
Bastiaens, Tim, Claes, Laurence, Claes, Stephan, De Clercq, Barbara, De Fruyt, Filip, De Hert, Marc, Dirk, Smits, Lowyck, Benedicte, Rossi, Gina, Vanwalleghem, Dominique, Vermote, Rudi   +10 more
core   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Community detection in networks using self-avoiding random walks

, 2018
Different kinds of random walks have proven to be useful in the study of structural properties of complex networks. Among them, the restricted dynamics of self-avoiding random walks (SAW), which visit only at most once each vertex in the same walk, has ...
Bagnato, Guilherme de Guzzi, Ronqui, José Ricardo Furlan, Travieso, Gonzalo   +2 more
core   +1 more source