Results 51 to 60 of about 2,811,176 (383)

A poset hierarchy

open access: yesOpen Mathematics, 2006
AbstractThis article extends a paper of Abraham and Bonnet which generalised the famous Hausdorff characterisation of the class of scattered linear orders. They gave an inductively defined hierarchy that characterised the class of scattered posets which do not have infinite incomparability antichains (i.e. have the FAC).
Džamonja, Mirna, Thompson, Katherine
openaire   +4 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Corps politiques, esprit de corps et pouvoir sur les corps chez Malebranche et Foucault

open access: yesAstérion
The theoretical dialogue that has been going on for many years between the philosophies of the modern period and the social sciences on the institutional structuring of the social body and the political body can shed light on the concept of ‘esprit de ...
Raffaele Carbone
doaj   +1 more source

Use of time indices while evaluating enterprises’ economic security

open access: yesВісник Житомирського державного технологічного університету: Серія: економіка, управління та адміністрування, 2019
The article substantiates that the main stage while evaluating both the separate constituent and the entire economic security of the enterprise is to evaluate the time, which makes the enterprise lag behind with ensuring this security component and ...
Ie.V. Mishchuk
doaj   +1 more source

A juridical-canonical perspective of internal criticism in the Church: Act of service or treason?

open access: yesChurch, Communication and Culture, 2022
In the last decade, we have witnessed a progressive increase in criticism of the Pope, the hierarchy, and the Roman Curia from within the Church itself.
Juan María Martínez Otero
doaj   +1 more source

Hierarchy of Gene Expression Data is Predictive of Future Breast Cancer Outcome [PDF]

open access: yes, 2013
We calculate measures of hierarchy in gene and tissue networks of breast cancer patients. We find that the likelihood of metastasis in the future is correlated with increased values of network hierarchy for expression networks of cancer-associated genes,
Chen, Man, Deem, Michael W.
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Bottom to Top Approach for Railway KPI Generation

open access: yesManagement Systems in Production Engineering, 2017
Railway maintenance especially on infrastructure produces a vast amount of data. However, having data is not synonymous with having information; rather, data must be processed to extract information.
Villarejo Roberto   +5 more
doaj   +1 more source

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