Results 51 to 60 of about 2,811,176 (383)
AbstractThis article extends a paper of Abraham and Bonnet which generalised the famous Hausdorff characterisation of the class of scattered linear orders. They gave an inductively defined hierarchy that characterised the class of scattered posets which do not have infinite incomparability antichains (i.e. have the FAC).
Džamonja, Mirna, Thompson, Katherine
openaire +4 more sources
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Corps politiques, esprit de corps et pouvoir sur les corps chez Malebranche et Foucault
The theoretical dialogue that has been going on for many years between the philosophies of the modern period and the social sciences on the institutional structuring of the social body and the political body can shed light on the concept of ‘esprit de ...
Raffaele Carbone
doaj +1 more source
Use of time indices while evaluating enterprises’ economic security
The article substantiates that the main stage while evaluating both the separate constituent and the entire economic security of the enterprise is to evaluate the time, which makes the enterprise lag behind with ensuring this security component and ...
Ie.V. Mishchuk
doaj +1 more source
A juridical-canonical perspective of internal criticism in the Church: Act of service or treason?
In the last decade, we have witnessed a progressive increase in criticism of the Pope, the hierarchy, and the Roman Curia from within the Church itself.
Juan María Martínez Otero
doaj +1 more source
Hierarchy of Gene Expression Data is Predictive of Future Breast Cancer Outcome [PDF]
We calculate measures of hierarchy in gene and tissue networks of breast cancer patients. We find that the likelihood of metastasis in the future is correlated with increased values of network hierarchy for expression networks of cancer-associated genes,
Chen, Man, Deem, Michael W.
core +1 more source
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Bottom to Top Approach for Railway KPI Generation
Railway maintenance especially on infrastructure produces a vast amount of data. However, having data is not synonymous with having information; rather, data must be processed to extract information.
Villarejo Roberto +5 more
doaj +1 more source

