Results 51 to 60 of about 224,204 (268)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Researching Capitalism In Poland: Economic Interests As A Cultural Construction
Journal of Management and Business Administration, Central Europe, 2019 Purpose: The three goals of the article are: first, to show some arguments surrounding the notion of capitalism in theoretical perspective, and also somewhat bashful connotations since it was intro-duced in Poland after the fall of communism; second, to ...
Witold Morawski
doaj +1 more source
Mechanisms for coordinating stakeholders of the higher education market: Theoretical approaches to identification [PDF]
Управленец, 2019 Massive shifts in public relations and enhancing interaction between stakeholders damage the effectiveness of standard coordination models through changing the architecture of business entities’ activity.
Vlasova N.Yu., Molokova E.L.
doaj +1 more source
Zeitschrift für Naturforschung A, 1983 Abstract The complexity of dynamical behavior possible in nonlinear (for example, electronic) systems depends only on the number of state variables involved. Single-variable dissipative dynamical systems (like the single-transistor flip-flop) can only possess point attractors.
openaire +2 more sources
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Temporal Hierarchy and Context-Dependence of Quorum Sensing Signal in Pseudomonas aeruginosa
Life, 2022 The Gram-negative bacterium Pseudomonas aeruginosa can cause infections in a broad range of hosts including plants, invertebrates and mammals and is an important source of nosocomial infections in humans.
Stoyko Katzarov, Volker Behrends
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Wage-setting in Belgium: Collective Autonomy under the Shadow of the Law
Italian Labour Law e-Journal, 2019 In this contribution, a brief outline of wage-setting in Belgium will be given. Wages will be contextualized as constituting an essential element of the employment relation.
Filip Dorssemont
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source