Results 41 to 50 of about 6,067 (209)

−254C>G SNP in the TRPC6 Gene Promoter Influences Its Expression via Interaction with the NF‐κB Subunit RELA in Steroid‐Resistant Nephrotic Syndrome Children

open access: yesInternational Journal of Genomics, Volume 2019, Issue 1, 2019., 2019
This study is aimed at exploring the mechanism by which the −254C>G single nucleotide polymorphism (SNP) on the transient receptor potential cation channel 6 (TRPC6) gene promoter could increase its activation in steroid‐resistant nephrotic syndrome children of China.
Xinyu Kuang   +6 more
wiley   +1 more source

Changes in the species composition and structure of the herb layer of a thermophilous oak forest subject to clear cutting

open access: yesActa Societatis Botanicorum Poloniae, 2014
Changes in the herb layer of a thermophilous oak forest (Potentillo albae-Quercetum), subject to clear cutting and artificial reforestation with Scotch pine monoculture, were analysed by a comparative method. It was found that cutting of a tree stand and
Hieronim Andrzejewski
doaj   +1 more source

Positive Selection of Squalene Synthase in Cucurbitaceae Plants

open access: yesInternational Journal of Genomics, Volume 2019, Issue 1, 2019., 2019
Triterpenoid saponins are secondary metabolites synthesized through isoprenoid pathways in plants. Cucurbitaceae represent an important plant family in which many species contain cucurbitacins as secondary metabolites synthesized through isoprenoid and triterpenoid pathways.
Jieying Qian   +9 more
wiley   +1 more source

Homocysteine Editing, Thioester Chemistry, Coenzyme A, and the Origin of Coded Peptide Synthesis †

open access: yesLife, 2017
Aminoacyl-tRNA synthetases (AARSs) have evolved “quality control” mechanisms which prevent tRNA aminoacylation with non-protein amino acids, such as homocysteine, homoserine, and ornithine, and thus their access to the Genetic Code. Of the ten AARSs that
Hieronim Jakubowski
doaj   +1 more source

Comparative Transcriptome Analysis in Eggplant Reveals Selection Trends during Eggplant Domestication

open access: yesInternational Journal of Genomics, Volume 2019, Issue 1, 2019., 2019
Eggplant (Solanum melongena L.) is an economically and nutritionally important fruit crop of the Solanaceae family, which was domesticated in India and southern China. However, the genome regions subjected to selective sweeps in eggplant remain unknown.
Qingzhen Wei   +8 more
wiley   +1 more source

Accumulation of Circulating Cell‐Free CpG‐Enriched Ribosomal DNA Fragments on the Background of High Endonuclease Activity of Blood Plasma in Schizophrenic Patients

open access: yesInternational Journal of Genomics, Volume 2019, Issue 1, 2019., 2019
Introduction. Schizophrenia (SZ) increases the level of cell death, leading to an increase in the concentration of circulating cell‐free DNA (cfDNA). Ribosomal DNA (rDNA) contains many unmethylated CpG motifs that stimulate TLR9‐MyD88‐NF‐κB signaling and the synthesis of proinflammatory cytokines. The number of rDNA copies in the genomes of SZ patients
E. S. Ershova   +14 more
wiley   +1 more source

Książe, „co krajowi byt swój poświęcił”. Portrety IX ordynata Ołyckiego, pułkownika Dominika Hieronima Radziwiłła (1786–1813) [PDF]

open access: yes, 2018
THE PRINCE, “WHO DEDICATED HIS LIFE FOR THE HOMELAND”. PORTRAITS OF COLONEL DOMINIK HIERONIM RADZIWIŁŁ (1786–1813) – THE IX ORDYNAT OF OLYKA. Dominik Hieronim Radziwiłł (1786–1813) was the last Ordynat of Olyka from the Nesvizh line.
Barczyk, Alina
core  

Enlightened Declarations: Ottoman and Russian Proclamations in the Ottoman‐Russian War of 1768–1774

open access: yesJournal for Eighteenth-Century Studies, Volume 47, Issue 3, Page 259-278, September 2024.
Abstract This article analyses the Ottoman and Russian proclamations during the Ottoman‐Russian War of 1768–1774 to understand their similarities and differences in discourse and their intended audiences, with a special focus on the elites of the Ottoman Empire.
Yusuf Ziya Karabıçak
wiley   +1 more source

Mutations in Homocysteine Metabolism Genes Increase Keratin N‐Homocysteinylation and Damage in Mice

open access: yesInternational Journal of Genomics, Volume 2018, Issue 1, 2018., 2018
Genetic or nutritional deficiencies in homocysteine (Hcy) metabolism increase Hcy‐thiolactone, which causes protein damage by forming isopetide bonds with lysine residues, generating N‐Hcy‐protein. In the present work, we studied the prevalence and genetic determinants of keratin damage caused by homocysteinylation.
Kamila Borowczyk   +6 more
wiley   +1 more source

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